Ogilvie Gina, Krajden Mel, Maginley Juanita, Isaac-Renton Judy, Hislop Greg, Elwood-Martin Ruth, Sherlock Chris, Taylor Darlene, Rekart Michael
British Columbia Centre for Disease Control, Vancouver, BC.
CMAJ. 2007 Aug 28;177(5):480-3. doi: 10.1503/cmaj.070013.
To study the feasibility of self-collected specimens for testing human papillomavirus (HPV) status among hard-to-reach women, outreach nurses recruited women in women's centres, shelters and alleys in Vancouver's Downtown Eastside. Of the 151 participants for whom samples were available, 43 (28.5%) tested positive for high-risk HPV. Outreach nurses were able to recontact 81.4% of the participants who tested positive and referred them for further testing. About 14% (21/151) of participants had never received a Papanicolaou smear in British Columbia, as compared with 8.3% (608/7336) of women in the BC general population (p < 0.05). This difference suggests that self-collection of specimens for HPV testing is a feasible method to reach women who have not previously participated in cervical cancer screening programs.
为研究自行采集样本检测难以接触到的女性人乳头瘤病毒(HPV)感染状况的可行性,外展护士在温哥华市中心东区的妇女中心、庇护所和小巷招募女性。在可获取样本的151名参与者中,43人(28.5%)高危HPV检测呈阳性。外展护士能够再次联系81.4%检测呈阳性的参与者,并将她们转介进行进一步检测。在不列颠哥伦比亚省,约14%(21/151)的参与者从未接受过巴氏涂片检查,而该省普通人群中这一比例为8.3%(608/7336)(p<0.05)。这一差异表明,自行采集样本进行HPV检测是接触此前未参与宫颈癌筛查项目女性的可行方法。