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“快速康复”与择期腹腔镜结直肠手术

["Fast-track" and elective, laparoscopic colo-rectal surgery].

作者信息

Widmaier U, Karrer M, Schoenberg M H

机构信息

Chirurgische Abteilung, Rotkreuz-Klinikum München, Deutschland.

出版信息

Zentralbl Chir. 2007 Aug;132(4):342-8; discussion 348-9. doi: 10.1055/s-2007-981204.

Abstract

UNLABELLED

The aim of this prospective clinical evaluation was to investigate the influence of "Fast-track"-treatment in patients undergoing laparoscopic colorectal operations and its effect on morbidity, hospital stay and recovery.

PATIENTS AND METHODS

Bowel cleaning under enteral hypercaloric nutrition (Biosorb Energie, Fa. Nutricia, Germany) was achieved with Fleet (Ferring Arzneimittel, Germany) one day prior to surgery. A peridural catheter was placed preoperatively. Intraoperative electrolyte substitution should not exceed 12 ml/kg KG/h. In case of decreasing intraoperative blood pressure hydroxyethylstarch 6% was substituted. The nasogastric tube was removed immediately after the operation, the urinary catheter was removed on the first postoperative day. The patients stayed on the intermediate care department for one night and started already there with oral feeding and mobilisation (for 2 h). The following days mobilisation increased to 4 h daily under normal enteral nutrition without infusions.

RESULTS

Between June 2003 and January 2006, 147 patients undergoing elective colorectal surgery were included in this study. Diverticulitis (n = 114), malignant tumors of the sigmoid colon (n = 6) or rectal cancer (n = 13), colonic adenomas (n = 5), stenotic Crohn's disease (n = 4) and small bowel carcinoid (n = 1), rectal prolaps (n = 1) and elongated colon sigmoideum (n = 4) were indications for surgical treatment. Laparoscopic sigmoid resection (n = 117), left hemicolectomy (n = 11), ileocecal resection (n = 8), anterior resection with total mesorectal excision (n = 9), abdomino-perineal exstirpation (n = 1) and anterior-segmental resection of the rectum (n = 1) were performed. Drainages were removed on the 2nd, peridural catheter on the 3rd postoperative day. Defecation occurred in all patients until the 2 (nd) postop. day. Early postoperative complication rate was 15% (22/147 patients) without mortality. 8 patients (5%) with anastomotic leakage were reoperated. The mean hospital stay was 6 days. The re-admission rate was 3% (4/147 patients) and included one patient with anastomotic leakage.

CONCLUSION

"Fast-track"-treatment in combination with minimal-invasive surgery is a safe and comfortable perioperative treatment for patients with elective colorectal operations.

摘要

未标注

本前瞻性临床评估的目的是研究“快速康复”治疗对接受腹腔镜结直肠手术患者的影响及其对发病率、住院时间和恢复情况的作用。

患者与方法

术前一天使用弗利特(德国费林制药)在肠内高热量营养(德国纽迪希亚公司的Biosorb Energie)支持下进行肠道清洁。术前放置硬膜外导管。术中电解质补充量每千克体重每小时不应超过12毫升。术中血压下降时,用6%羟乙基淀粉进行补充。术后立即拔除鼻胃管,术后第一天拔除尿管。患者在中间护理病房停留一晚,在那里即开始口服进食并活动(2小时)。接下来的日子里,在正常肠内营养且无输液的情况下,活动量增加至每天4小时。

结果

2003年6月至2006年1月,147例接受择期结直肠手术的患者纳入本研究。手术治疗的适应证包括憩室炎(n = 114)、乙状结肠恶性肿瘤(n = 6)或直肠癌(n = 13)、结肠腺瘤(n = 5)、狭窄性克罗恩病(n = 4)和小肠类癌(n = 1)、直肠脱垂(n = 1)以及乙状结肠冗长(n = 4)。实施了腹腔镜乙状结肠切除术(n = 117)、左半结肠切除术(n = 11)、回盲部切除术(n = 8)、全直肠系膜切除的前切除术(n = 9)、腹会阴联合切除术(n = 1)以及直肠前节段切除术(n = 1)。术后第2天拔除引流管,术后第3天拔除硬膜外导管。所有患者在术后第2天之前均排便。术后早期并发症发生率为15%(22/147例患者),无死亡病例。8例(5%)发生吻合口漏的患者接受了再次手术。平均住院时间为6天。再入院率为3%(4/147例患者),其中包括1例吻合口漏患者。

结论

“快速康复”治疗联合微创手术对于接受择期结直肠手术的患者是一种安全且舒适的围手术期治疗方法。

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