Richter J, Jirman J, Havlícek J, Hrdina R
Department of Technology of Organic Compunds, Faculty of Chemical Technology, Univerzity of Pardubice, Czech Republic.
Pharmazie. 2007 Aug;62(8):580-4.
Methods of preparation of API pioglitazone were discussed from the point of view of impurities occurrence. Four real impurities (I-IV) of pioglitazone were prepared and characterized by means of NMR spectroscopy.