Kuhn Jens, Lenartz Doris, Huff Wolfgang, Lee SunHee, Koulousakis Athanasios, Klosterkoetter Joachim, Sturm Volker
Department of Psychiatry and Psychotherapy, University of Cologne, Kerpener Strasse 62, 50924 Cologne, Germany.
J Neurol Neurosurg Psychiatry. 2007 Oct;78(10):1152-3. doi: 10.1136/jnnp.2006.113092.
Chronic consumption of alcohol represents one of the greatest health and socioeconomic problems worldwide. We report on a 54-year-old patient with a severe anxiety disorder and secondary depressive disorder in whom bilateral deep brain stimulation (DBS) of the nucleus accumbens was carried out. Despite the absence of desired improvement in his primary disorder, we observed a remarkable although not primarily intended alleviation of the patient's comorbid alcohol dependency. Our case report demonstrates the extremely effective treatment of alcohol dependency by means of DBS of the nucleus accumbens and may reveal new prospects in overcoming therapy resistance in dependencies in general.
长期饮酒是全球最严重的健康和社会经济问题之一。我们报告了一名54岁患有严重焦虑症和继发性抑郁症的患者,对其进行了伏隔核双侧深部脑刺激(DBS)治疗。尽管其原发性疾病未得到预期改善,但我们观察到患者共病的酒精依赖得到了显著缓解,尽管这并非主要治疗目的。我们的病例报告证明了通过伏隔核DBS对酒精依赖进行的极其有效的治疗,并可能揭示在克服一般成瘾性治疗抵抗方面的新前景。