Wyatt Christina M, Winston Jonathan A, Malvestutto Carlos D, Fishbein Dawn A, Barash Irina, Cohen Alan J, Klotman Mary E, Klotman Paul E
Department of Medicine, Division of Nephrology, Mount Sinai School of Medicine, New York, NY, USA.
AIDS. 2007 Oct 1;21(15):2101-3. doi: 10.1097/QAD.0b013e3282ef1bb4.
Kidney disease is an important complication of HIV, particularly in minority populations. We describe the burden of chronic kidney disease among 1239 adults followed at an urban AIDS center, with an estimated prevalence of 15.5% (n = 192). Independent predictors of kidney disease included older age, black race, hepatitis C virus exposure, and lower CD4 cell count. These data suggest that chronic kidney disease remains a common complication of HIV infection in the era of antiretroviral therapy.
肾脏疾病是艾滋病毒的一种重要并发症,在少数族裔人群中尤为如此。我们描述了一家城市艾滋病中心随访的1239名成年人中慢性肾脏病的负担,估计患病率为15.5%(n = 192)。肾脏疾病的独立预测因素包括年龄较大、黑人种族、丙型肝炎病毒暴露和较低的CD4细胞计数。这些数据表明,在抗逆转录病毒治疗时代,慢性肾脏病仍然是艾滋病毒感染的常见并发症。