Wallien Madeleine S C, Swaab Hanna, Cohen-Kettenis Peggy T
Ms. Wallien is with the Department of Medical Psychology and Institute for Clinical and Experimental Neurosciences, Graduate School of Neurosciences, at the VU University Medical Center, Amsterdam, The Netherlands; Dr. Swaab is with the Department of Education and Child Studies, Subdepartment Clinical Child and Adolescent Studies, Leiden University, Leiden, The Netherlands; and Dr. Cohen-Kettenis is with the Department of Medical Psychology at the VU University Medical Center, Amsterdam.
Ms. Wallien is with the Department of Medical Psychology and Institute for Clinical and Experimental Neurosciences, Graduate School of Neurosciences, at the VU University Medical Center, Amsterdam, The Netherlands; Dr. Swaab is with the Department of Education and Child Studies, Subdepartment Clinical Child and Adolescent Studies, Leiden University, Leiden, The Netherlands; and Dr. Cohen-Kettenis is with the Department of Medical Psychology at the VU University Medical Center, Amsterdam.
J Am Acad Child Adolesc Psychiatry. 2007 Oct;46(10):1307-1314. doi: 10.1097/chi.0b013e3181373848.
To investigate the prevalence and type of comorbidity in children with gender identity disorder (GID).
The Diagnostic Interview Schedule for Children-Parent version was used to assess psychopathology according to the DSM in two groups of children. The first group consisted of 120 Dutch children (age range 4-11 years) who were referred to a gender identity clinic between 1998 and 2004 (GID group) and the second group consisted of 47 Dutch children who were referred to an attention-deficit/hyperactivity disorder (ADHD) clinic between 1998 and 2004 (ADHD group; 100% response rate for both groups).
Fifty-two percent of the children diagnosed with GID had one or more diagnoses other than GID. As expected, more internalizing (37%) than externalizing (23%) psychopathology was present in both boys and girls. Furthermore, the odds ratios of having internalizing or externalizing comorbidity were 1.28 and 1.39 times higher, respectively, in the clinical comparison group (ADHD group) than in the GID group. Finally, 31% of the children with GID suffered from an anxiety disorder.
The results of this categorical diagnostic study show that children with GID are at risk for developing co-occurring problems. Because 69% of the children do not have an anxiety disorder, a full-blown anxiety disorder does not seem to be a necessary condition for the development of GID. Clinicians working with children with GID should be aware of the risk for co-occurring psychiatric problems and must realize that externalizing comorbidity, if present, can make a child with GID more vulnerable to social ostracism.
调查性别认同障碍(GID)儿童共病的患病率及类型。
采用儿童-家长版诊断访谈量表,根据《精神疾病诊断与统计手册》(DSM)对两组儿童进行精神病理学评估。第一组由120名荷兰儿童(年龄范围4至11岁)组成,他们于1998年至2004年间被转诊至一家性别认同诊所(GID组);第二组由47名荷兰儿童组成,他们于1998年至2004年间被转诊至一家注意力缺陷多动障碍(ADHD)诊所(ADHD组;两组的应答率均为100%)。
被诊断为GID的儿童中,52%有一项或多项除GID之外的诊断。不出所料,男孩和女孩中内化性精神病理学(37%)均多于外化性精神病理学(23%)。此外,在临床比较组(ADHD组)中,出现内化性或外化性共病的比值比分别比GID组高1.28倍和1.39倍。最后,31%的GID儿童患有焦虑症。
这项分类诊断研究的结果表明,GID儿童有出现共病问题的风险。由于69%的儿童没有焦虑症,全面发作的焦虑症似乎不是GID发生的必要条件。治疗GID儿童的临床医生应意识到共发精神问题的风险,并且必须认识到,如果存在外化性共病,会使GID儿童更容易受到社会排斥。