Ota Nobuko, Maeshima Shinichiro, Osawa Aiko, Kawarada Miho, Tanemura Jun
Graduate School of Health Science and Technology, Kawasaki University of Medical Welfare, 288 Matsushima, Kurashiki-city, Okayama 701-0193, Japan.
Brain Nerve. 2007 Sep;59(9):991-6.
We report here a case of amnestic syndrome with executive dysfunction and attention deficit caused by cerebral infarction in the right temporal lobe was reported. An 80-year-old, right-handed female with complaints of memory impairment, was admitted to our hospital. She had neither motor paresis nor sensory disturbances. She exhibited disorientation, retrograde amnesia, anterograde amnesia, executive dysfunction and attention deficit. Although her immediate recall and remote memory were almost intact, her recent memory was moderately impaired. Both verbal memory and non-verbal memory were impaired. Brain MRI revealed cerebral infarction in the right temporal lobe involving the parahippocampal gyrus, and SPECT demonstrated low perfusion areas in both the cerebral hemispheres involving basal ganglia and the right thalamus. After a 4-month rehabilitation program, her memory impairment improved considerably. We consider that the reason that contributed to these improvement include the fact that her lesion was unilateral and that her executive dysfunction and attention deficit also improved. This finding suggests that memory is related to attention and executive function.
我们在此报告一例由右侧颞叶脑梗死引起的伴有执行功能障碍和注意力缺陷的遗忘综合征病例。一名80岁右利手女性因记忆障碍入院。她既无运动性轻瘫也无感觉障碍。她表现出定向障碍、逆行性遗忘、顺行性遗忘、执行功能障碍和注意力缺陷。尽管她的即刻回忆和远期记忆几乎完好无损,但近期记忆有中度受损。言语记忆和非言语记忆均受损。脑部MRI显示右侧颞叶脑梗死累及海马旁回,SPECT显示双侧大脑半球包括基底神经节和右侧丘脑存在低灌注区。经过4个月的康复治疗,她的记忆障碍有了显著改善。我们认为促成这些改善的原因包括她的病变是单侧的,以及她的执行功能障碍和注意力缺陷也有所改善。这一发现表明记忆与注意力和执行功能有关。