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人类胃肠道中乳酸杆菌的黏附因子。

Adherence factors of Lactobacillus in the human gastrointestinal tract.

作者信息

Vélez Mónica Perea, De Keersmaecker Sigrid C J, Vanderleyden Jos

机构信息

Centre of Microbial and Plant Genetics, K.U. Leuven, Leuven, Belgium.

出版信息

FEMS Microbiol Lett. 2007 Nov;276(2):140-8. doi: 10.1111/j.1574-6968.2007.00908.x. Epub 2007 Sep 19.

Abstract

Despite the increasing number of scientific reports describing adhesion of Lactobacillus to components of the human intestinal mucosa, information on the surface molecules mediating this adhesion and their corresponding receptors is fragmentary. This MiniReview compiles present knowledge of the genetically and functionally characterized Lactobacillus factors responsible for mediating adhesion to different components of the human gastrointestinal tract. In addition, for the proteins among these factors, the domain structure is discussed, and where appropriate the results of in silico analyses are reported.

摘要

尽管描述乳酸杆菌与人肠道黏膜成分黏附的科学报告数量不断增加,但关于介导这种黏附的表面分子及其相应受体的信息却支离破碎。本综述汇编了目前关于负责介导与人类胃肠道不同成分黏附的具有遗传和功能特征的乳酸杆菌因子的知识。此外,对于这些因子中的蛋白质,还讨论了其结构域结构,并在适当的地方报告了计算机分析的结果。

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