Nassi N, Piumelli R, Lombardi E, Landini L, Donzelli G, de Martino M
Department of Pediatrics, University of Florence, Anna Meyer Children's University Hospital, Florence, Italy.
Arch Dis Child. 2008 Feb;93(2):126-32. doi: 10.1136/adc.2007.118513. Epub 2007 Sep 24.
To compare transthoracic impedance (TTI/ECG) and pulse oximetry alarm traces detected during home monitoring in infants at risk of apnoea, bradycardia and hypoxaemia.
A retrospective evaluation of the monitor downloads of 67 infants who had undergone either TTI/ECG or pulse oximetry home monitoring using a device which can detect both parameters.
The patients were categorised as: apparent life-threatening events (n = 39), preterm infants (n = 21) and miscellaneous (n = 7). TTI/ECG and pulse oximetry alarm traces were scored as either true or false alarms. Classification criteria were based on visual analysis of the impedance and plethysmographic waveforms captured by the memory monitor every time alarm thresholds were violated.
5242 alarms occurred over 3452 days of monitoring: 4562 (87%) were false and 680 (13%) true. The mean duration of monitoring was 51 days (range 5-220 days). There were 2982 TTI/ECG false alarms (65% of the total) and 1580 pulse oximetry false alarms (35%) (p = 0.0042). Of the 680 true alarms, 507 (74%) were desaturations not attributable to central apnoea and 173 (26%) were true TTI/ECG alarms (p = 0.0013).
Comparison of pulse oximetry and TTI/ECG alarm traces shows that true events were mostly attributable to desaturations, while false alarms were mainly provoked by TTI/ECG. The total number of false alarms is lower than reported in other studies using TTI/ECG only, thus indicating that monitoring using both pulse oximetry and TTI/ECG is suitable for home use. When the combination of both techniques is not feasible or not required, we recommend the use of motion resistant pulse oximetry alone.
比较经胸阻抗(TTI/心电图)和脉搏血氧饱和度监测在有呼吸暂停、心动过缓和低氧血症风险的婴儿家庭监测期间检测到的警报轨迹。
对67例使用可检测两种参数的设备进行TTI/心电图或脉搏血氧饱和度家庭监测的婴儿的监测数据下载进行回顾性评估。
将患者分为:明显危及生命事件(n = 39)、早产儿(n = 21)和其他(n = 7)。TTI/心电图和脉搏血氧饱和度警报轨迹分为真警报或假警报。分类标准基于每次超过警报阈值时由存储监测器捕获的阻抗和容积描记波形的视觉分析。
在3452天的监测中发生了5242次警报:4562次(87%)为假警报,680次(13%)为真警报。平均监测时长为51天(范围5 - 220天)。有2982次TTI/心电图假警报(占总数的65%)和1580次脉搏血氧饱和度假警报(35%)(p = 0.0042)。在680次真警报中,507次(74%)为非中枢性呼吸暂停导致的血氧饱和度下降,173次(26%)为真TTI/心电图警报(p = 0.0013)。
脉搏血氧饱和度和TTI/心电图警报轨迹的比较表明,真实事件大多归因于血氧饱和度下降,而假警报主要由TTI/心电图引发。假警报总数低于仅使用TTI/心电图的其他研究报告,因此表明同时使用脉搏血氧饱和度和TTI/心电图进行监测适用于家庭使用。当两种技术的组合不可行或不需要时,我们建议单独使用抗运动脉搏血氧饱和度监测。