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一种用于检测活细胞射频解调的双共振腔。

A doubly resonant cavity for detection of RF demodulation by living cells.

作者信息

Balzano Quirino, Hodzic Vildana, Gammon Robert W, Davis Christopher C

机构信息

Department of Electrical and Computer Engineering, University of Maryland, College Park, Maryland 20742, USA.

出版信息

Bioelectromagnetics. 2008 Feb;29(2):81-91. doi: 10.1002/bem.20365.

Abstract

We describe the design, construction, and operating characteristics of a doubly resonant cylindrical microwave cavity. This cavity has been developed to allow a search for nonlinear RF energy conversion in biological cells. Cells with a diode-like nonlinearity could demodulate a modulated RF carrier wave and generate low frequency signals in an exposed biological preparation. The cavity is designed to be resonant on the TE(111) mode at about 890 MHz and on the TE(113) mode at about 1780 MHz. The cavity performs exactly as designed and has proved capable of detecting the nonlinearity in a microscopic Schottky diode test structure. The sensitivity is sufficient to detect any nonlinearity in a collection of biological cells that could have any potential biological significance.

摘要

我们描述了一种双共振圆柱形微波腔的设计、构造及运行特性。开发此腔是为了探寻生物细胞中的非线性射频能量转换。具有二极管样非线性特性的细胞能够解调调制射频载波,并在暴露的生物制剂中产生低频信号。该腔被设计为在约890兆赫兹的TE(111)模式和约1780兆赫兹的TE(113)模式下共振。该腔的运行与设计完全一致,并且已证明能够检测微观肖特基二极管测试结构中的非线性。其灵敏度足以检测生物细胞集合中任何可能具有潜在生物学意义的非线性。

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