Ko Changhong, Hsung Richard P, Al-Rashid Ziyad F, Feltenberger John B, Lu Ting, Yang Jin-Haek, Wei Yonggang, Zificsak Craig A
Division of Pharmaceutical Sciencies and Department of Chemistry, Rennebohm Hall 777 Highland Avenue, University of Wisconsin, Madison, Wisconsin 53705-2222, USA.
Org Lett. 2007 Oct 25;9(22):4459-62. doi: 10.1021/ol701768n. Epub 2007 Oct 2.
A stereoselective halo-etherification of chiral enamides is described here. This work provides an approach to halogen containing cyclic ethers and reveals further mechanistic insights to the chemistry of chiral enamides.
本文描述了手性烯酰胺的立体选择性卤代醚化反应。这项工作提供了一种合成含卤环状醚的方法,并对手性烯酰胺的化学性质有了更深入的机理认识。