Thomson F J, Benbow E W, McMahon R F, Cheshire C M
Department of Medicine for the Elderly, Manchester Royal Infirmary.
J Clin Pathol. 1991 Dec;44(12):1034-6. doi: 10.1136/jcp.44.12.1034.
Pulmonary and myocardial damage are frequently cited as manifestations of disseminated intravascular coagulation (DIC), but rarely as causes. Three elderly cases of severe DIC due to pulmonary and myocardial infarction are reported. All three patients died. Necropsy showed extensive pulmonary emboli in each case with large pulmonary infarcts in cases 1 and 2 and a ventricular aneurysm containing thrombus in cases 2 and 3. Early diagnosis and treatment of pulmonary embolism requires a high degree of clinical suspicion but may prevent progression to the irreversible stage of severe DIC.
肺和心肌损伤常被认为是弥散性血管内凝血(DIC)的表现,但很少被视为病因。本文报告了3例因肺和心肌梗死导致严重DIC的老年病例。所有3例患者均死亡。尸检显示,每例均有广泛的肺栓塞,病例1和病例2有大面积肺梗死,病例2和病例3有含血栓的心室壁瘤。肺栓塞的早期诊断和治疗需要高度的临床怀疑,但这可能会防止病情发展到严重DIC的不可逆阶段。