Briken Peer, Kafka Martin P
Institute for Sex Research and Forensic Psychiatry, University Medical Centre Hamburg-Eppendorf, Hamburg, Germany.
Curr Opin Psychiatry. 2007 Nov;20(6):609-13. doi: 10.1097/YCO.0b013e3282f0eb0b.
This review addresses testosterone-lowering and other psychotropic medications for the treatment of paraphilic patients or sexual offenders.
Randomized controlled studies are still lacking, and only a few new studies were reported during the past year. On the other hand, there is substantial scientific knowledge about the wide range of psychiatric comorbidity associated with paraphilias and in sexual offenders. Empirically based treatment of these patients, especially of impulsivity, anxiety and mood disorders, may also ameliorate sexual impulsivity.
Medication interventions, either substantially lowering serum testosterone or treating axis I comorbidities, show definite promise as a significant component of the management of sexual offenders. Pharmacotherapy should be combined with other therapeutic treatment modalities, most commonly cognitive-behaviour based psychotherapy and intensive community supervision.
本综述探讨降低睾酮水平的药物及其他精神药物在治疗性偏好障碍患者或性犯罪者中的应用。
目前仍缺乏随机对照研究,过去一年仅报道了少数新研究。另一方面,关于性偏好障碍及性犯罪者所伴发的广泛精神共病,已有大量科学认识。对这些患者进行基于实证的治疗,尤其是针对冲动、焦虑和情绪障碍的治疗,也可能改善性冲动。
大幅降低血清睾酮水平或治疗轴I共病的药物干预,作为性犯罪者管理的重要组成部分显示出明确前景。药物治疗应与其他治疗方式相结合,最常见的是基于认知行为的心理治疗和强化社区监管。