Suppr超能文献

[双侧子宫动脉栓塞术治疗子宫平滑肌瘤:最新进展]

[Treatment of uterine fibromyoma with bilateral uterine artery embolization: state of the art].

作者信息

Lupattelli T, Clerissi J, Basile A, Minnella D P, Donati Sarti R, Gerli S, Di Renzo G

机构信息

Dipartimento di Radiologia Interventistica, Multimedica Holding, Sesto San Giovanni, Milano.

出版信息

Minerva Ginecol. 2007 Aug;59(4):427-39.

Abstract

Uterine fibroids are common tumors of the female pelvis. Uterine artery embolization (UAE) is a minimally invasive alternative procedure in appropriate candidates to conventional myomectomy and hysterectomy for symptomatic uterine leiomyoma, reducing or eliminating leiomyoma-related symptoms of bleeding, bulk, and/or pain. In order to completely block the arterial blood supply to the fibroid, UAE is typically performed in both uterine arteries. At 1 year follow-up, the uterus may shrink by up to 55%, however, a re-growth of the fibroid may occur. The rate of major complications and amenorrhea following this procedure is low, ranging in most series from 1% to 3.5% and 1% to 7%, respectively. Nevertheless, the rate of amenorrhea in women over 45 seems to be higher. Women who wish to become pregnant should be cautioned about potential complications during pregnancy. Despite the lack of controlled studies that compared UAE with conventional surgery, and despite limited extended outcome data, UAE has gained rapid acceptance, primarily because this procedure preserves the uterus, is less invasive, and has less short-term morbidity than most surgical options. This review focuses on recent publications evaluating UAE and concludes that it is a safe treatment option, providing substantial improvement in both health-related quality of life and symptom control for most patients, with a very low rate of major complications. Any centre that offers UAE should adhere to published clinical guidelines, maintain ongoing assessment of quality improvement measures, and observe strict criteria to obtain procedural privileges. The gynecologist is likely to be the primary initial consultant to patients who present with myomas symptoms. Therefore, they must be familiar with the indications, exclusions, outcome expectations, and complications of UAE. When hysterectomy is the only option, UAE should be seriously taken into consideration. At this particular moment in time, data are needed from randomized controlled trials comparing UAE with surgical procedures. Current efforts to provide prospective objective assessment of treatment outcomes and complications after UAE will help to optimize women options and clinical guidelines.

摘要

子宫肌瘤是女性盆腔常见的肿瘤。子宫动脉栓塞术(UAE)是一种微创替代手术,适用于有症状的子宫平滑肌瘤患者,可替代传统的肌瘤切除术和子宫切除术,能减轻或消除与肌瘤相关的出血、肿块和/或疼痛症状。为了完全阻断肌瘤的动脉血供,UAE通常在双侧子宫动脉进行。在1年的随访中,子宫可能缩小达55%,然而,肌瘤可能会复发。该手术后主要并发症和闭经的发生率较低,在大多数系列研究中分别为1%至3.5%和1%至7%。尽管如此,45岁以上女性的闭经发生率似乎更高。希望怀孕的女性应被告知妊娠期间的潜在并发症。尽管缺乏将UAE与传统手术进行比较的对照研究,且长期结果数据有限,但UAE已迅速得到认可,主要是因为该手术保留了子宫,侵入性较小,且短期发病率低于大多数手术选择。本综述重点关注近期评估UAE的出版物,并得出结论,它是一种安全的治疗选择,能显著改善大多数患者的健康相关生活质量并控制症状,主要并发症发生率极低。任何提供UAE的中心都应遵循已发表的临床指南,持续评估质量改进措施,并遵守严格标准以获得手术特权。妇科医生可能是出现肌瘤症状患者的首要初始咨询医生。因此,他们必须熟悉UAE的适应症、排除标准、预期结果和并发症。当子宫切除术是唯一选择时,应认真考虑UAE。目前,需要来自比较UAE与手术程序的随机对照试验的数据。当前对UAE治疗结果和并发症进行前瞻性客观评估的努力将有助于优化女性的选择和临床指南。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验