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社区药房发现的药物相关问题调查。

Survey of drug-related problems identified by community pharmacies.

作者信息

Hämmerlein Andrea, Griese Nina, Schulz Martin

机构信息

Center for Drug Information and Pharmacy Practice, ABDA-Federal Union of German Associations of Pharmacists, Berlin, Germany.

出版信息

Ann Pharmacother. 2007 Nov;41(11):1825-32. doi: 10.1345/aph.1K207. Epub 2007 Oct 9.

Abstract

BACKGROUND

A drug-related problem (DRP) is defined as an event or circumstance that actually or potentially interferes with desired health outcomes. DRPs can lead to ineffective pharmacotherapy and may cause drug-related morbidity and mortality. Most DRPs are avoidable and community pharmacies are assuming an active role in preventing and solving DRPs.

OBJECTIVE

To identify the spectrum of DRPs encountered in community pharmacies.

METHODS

In 2005, a nationwide survey in Germany was conducted in community pharmacies to record all identified DRPs. Participating community pharmacies were free to select one week within the designated study period (February-May) and were instructed to record basic statistics (eg, number of patient interactions, number of prescriptions filled/nonprescription [over-the-counter; OTC] drugs dispensed per week), as well as patient-, problem-, and intervention-related data (eg, patient age and sex, whether a prescription-only or OTC drug was involved in the DRP, the time needed for problem resolution). DRPs were categorized using a modified version of the PI-Doc (problem-intervention-documentation) classification system.

RESULTS

Community pharmacies that participated in the study (N = 1146) documented 10,427 DRPs (9.1 DRP per pharmacy per week). A broad spectrum of DRPs was identified, with 9 of 10 cases involving prescribed medicines. DRPs arose on 3 primary levels: the prescription-, the patient-, and the delivery level. Overall, drug-drug interactions were the most frequently reported DRP (8.6%) and, according to community pharmacies, more than 80% of identified DRPs could be resolved completely. The prescribing physician was contacted in 60.5% of all such cases. Median time needed for solving a DRP was 5 minutes.

CONCLUSIONS

Pharmacists in the community pharmacy setting are well suited to identify and resolve DRPs. Ensuring the proper use of both prescription and OTC drugs is one of the basic responsibilities of pharmacists. This specific role of pharmacists within the healthcare system needs to be more fully recognized.

摘要

背景

药物相关问题(DRP)被定义为实际或潜在干扰预期健康结果的事件或情况。DRP可导致药物治疗无效,并可能引起与药物相关的发病率和死亡率。大多数DRP是可以避免的,社区药房在预防和解决DRP方面发挥着积极作用。

目的

确定社区药房中遇到的DRP范围。

方法

2005年,在德国社区药房进行了一项全国性调查,以记录所有已识别的DRP。参与调查的社区药房可在指定研究期间(2月至5月)内自由选择一周,并被要求记录基本统计数据(如患者互动次数、每周调配的处方/非处方[非处方药;OTC]药物数量),以及与患者、问题和干预相关的数据(如患者年龄和性别、DRP中涉及的是处方药还是OTC药物、解决问题所需时间)。使用PI-Doc(问题-干预-记录)分类系统的修改版本对DRP进行分类。

结果

参与研究的社区药房(N = 1146)记录了10427例DRP(每家药房每周9.1例DRP)。识别出了广泛的DRP范围,十分之九的案例涉及处方药。DRP出现在三个主要层面:处方层面、患者层面和配送层面。总体而言,药物相互作用是最常报告的DRP(8.6%),并且根据社区药房的说法,超过80%已识别的DRP可以完全解决。在所有此类案例中,60.5%的情况联系了开处方的医生。解决一个DRP所需的中位时间为5分钟。

结论

社区药房的药剂师非常适合识别和解决DRP。确保正确使用处方药和OTC药物是药剂师的基本职责之一。药剂师在医疗保健系统中的这一特定作用需要得到更充分的认可。

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