[一种由蜂毒制成的用于蜜蜂蛰伤过敏反应特异性诊断的新型苏联过敏原]

[A new Soviet allergen made from bee venom for the specific diagnosis of allergic reactions to bee stings].

作者信息

Shvets S M, Gushchin I S, Poroshina Iu A, Chitaeva V G, Titova S M, Romanova E B, Korneva N V, Orlov B N, Lebedin Iu S

出版信息

Ter Arkh. 1991;63(8):108-10.

Abstract

Overall 46 patients with allergic reactions to bee stings were examined. As a result of making skin prick, scarification and intracutaneous tests with an allergen from bee venom, allergy to bee stings was revealed in all the 46 patients, whereas only 37 patients responded to an allergen from the bee body. Specific IgE-antibodies using RAST were detected in 29 out of 31 patients. All the 29 patients had positive skin tests with an allergen from bee venom and only 22 with an allergen from the bee body. Specific histamine release was detected in all 13 patients examined by means of the indicated test. 100% coincidence was recorded with the results of intracutaneous tests with an allergen from bee venom. Only 11 out of the 13 patients had positive intracutaneous tests with an allergen from the bee body. Thus, the new Soviet allergen obtained from bee venom is effective in the diagnosis of allergy in response to bee stings.

摘要

共对46例对蜂蜇过敏的患者进行了检查。通过用蜂毒过敏原进行皮肤点刺、划痕和皮内试验，发现所有46例患者均对蜂蜇过敏，而只有37例患者对蜂体过敏原产生反应。采用放射变应原吸附试验（RAST）在31例患者中的29例检测到特异性IgE抗体。所有29例患者对蜂毒过敏原的皮肤试验呈阳性，而对蜂体过敏原皮肤试验呈阳性的仅22例。通过上述试验对所有13例受检患者均检测到特异性组胺释放。其结果与用蜂毒过敏原进行皮内试验的结果100%相符。13例患者中只有11例对蜂体过敏原的皮内试验呈阳性。因此，从蜂毒中提取的新型苏联过敏原在诊断蜂蜇过敏方面是有效的。