Powers J M, Liu Y, Hair L S, Kascsack R J, Lewis L D, Levy L A
Department of Pathology, Columbia-Presbyterian Medical Center, New York, NY.
Acta Neuropathol. 1991;83(1):95-8. doi: 10.1007/BF00294437.
We report a 69-year-old female with cerebral and cerebellar symptomatology of 15-month duration. At autopsy, both panencephalopathic Creutzfeldt-Jakob and plaque-predominant Alzheimer diseases were found. Plaque amyloid was exclusively of the beta/A4 type, but abundant abnormal protease-resistant protein was identified by Western blot analysis of brain extracts.
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