Nogawa Masamichi, Yamakoshi Takehiro, Ikarashi Akira, Tanaka Shinobu, Yamakoshi Ken-ichi
Kanazawa University Graduate School of Natural Science & Technology.
Conf Proc IEEE Eng Med Biol Soc. 2006;Suppl:6537-9. doi: 10.1109/IEMBS.2006.260886.
In order to develop a simple and reliable assessment method of the stress induced psychosomatic and hemodynamic responses against various stress situations, especially for evaluating of the effectiveness of stress reduction methods, a multipurpose non-invasive continuous cardiovascular monitoring system was developed. The monitoring system could measure beat-by-beat finger blood pressure (SBP, MBP, DBP based on the volume-compensation method), cardiac output (CO, electrical admittance method), total peripheral resistance (TPR=MBP/CO), and the other hemodynamic related parameters (e.g. RR-interval, respiratory rate, pulse wave velocity, etc.). As controlled stress conditions, the human subjects would be exposed to the various stresses such as flash video display, electrical stimulation and so on. In this study, after 5 minutes resting, the stress induced hemodynamic responses were measured during 10-min presentation of floating vertical stripes image using 5 healthy subjects. The image presentation was discontinued when the subject gave his/her self-assessment due to considerable discomfort. The results showed that although BP increased during the presentation in all the subjects, there observed two types of cardiovascular responses; one is a type of increase in CO (or of almost unchanging or decrease in TRP), and the other of increase in TPR. These results strongly suggested that the detection of the change in TPR might be an important factor for the evaluation of stress conditions. Further investigations would be required for the reasons why these two types were observed in the same stressful condition.
为了开发一种简单可靠的评估方法,用于评估针对各种应激情况所诱发的身心和血液动力学反应,特别是用于评估减压方法的有效性,我们开发了一种多功能非侵入性连续心血管监测系统。该监测系统能够逐搏测量手指血压(基于容积补偿法的收缩压、平均血压、舒张压)、心输出量(心输出量,电阻抗法)、总外周阻力(总外周阻力=平均血压/心输出量)以及其他与血液动力学相关的参数(例如RR间期、呼吸频率、脉搏波速度等)。作为受控应激条件,人类受试者将暴露于各种应激源,如闪烁视频显示、电刺激等。在本研究中,5名健康受试者在休息5分钟后,在呈现漂浮垂直条纹图像的10分钟期间测量应激诱发的血液动力学反应。当受试者因明显不适而进行自我评估时,图像呈现停止。结果表明,虽然在所有受试者的呈现过程中血压都有所升高,但观察到两种类型的心血管反应;一种是心输出量增加(或总外周阻力几乎不变或降低),另一种是总外周阻力增加。这些结果强烈表明,检测总外周阻力的变化可能是评估应激状况的一个重要因素。对于在相同应激条件下观察到这两种类型的原因,还需要进一步研究。