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脊髓脂肪瘤:临床谱、胚胎学及治疗

Spinal lipomas: clinical spectrum, embryology, and treatment.

作者信息

Finn Michael A, Walker Marion L

机构信息

Department of Neurosurgery, Division of Pediatric Neurosurgery, Primary Children's Medical Center, University of Utah, Salt Lake City, Utah 84113, USA.

出版信息

Neurosurg Focus. 2007;23(2):E10. doi: 10.3171/FOC-07/08/E10.

Abstract

Spinal lipomas, particularly lipomas of the conus medullaris and terminal filum, are the most common form of occult spinal dysraphism and represent a wide spectrum of disease with regard to anatomy, clinical presentation, and treatment options. These lesions, however, are united by a similar embryology and pathological mechanism by which symptoms arise. Recently, the treatment of these lesions has generated much controversy, with some physicians advocating surgical treatment for all patients regardless of symptoms and others proposing that surgery be withheld until symptoms develop. The authors discuss lumbosacral spinal lipomas, with particular attention to the theories of their origin, anatomical and pathological features, and treatment options, including a review of current controversies.

摘要

脊髓脂肪瘤,尤其是圆锥和终丝脂肪瘤,是隐性脊柱裂最常见的形式,在解剖结构、临床表现和治疗选择方面代表了广泛的疾病谱。然而,这些病变通过相似的胚胎学和病理机制产生症状而相互关联。最近,这些病变的治疗引发了诸多争议,一些医生主张对所有患者进行手术治疗,无论其有无症状,而另一些医生则建议在症状出现之前不进行手术。作者讨论了腰骶部脊髓脂肪瘤,特别关注其起源理论、解剖和病理特征以及治疗选择,包括对当前争议的综述。

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