Adams D B, Harvey T S, Anderson M C
Department of Surgery, Medical University of South Carolina, Charleston 29425.
Am Surg. 1991 Jan;57(1):29-33.
Pancreatic pseudocysts represent a complication of severe pancreatic inflammatory disease. Although operative drainage is the cornerstone of therapy for pseudocysts, we have undertaken percutaneous catheter drainage in a selected group of 28 patients over a six-year period (1982-88). This represents 42 per cent of pseudocyst patients managed by the senior author and 1.7 per cent of admissions for pancreatitis at the Medical University Hospitals during that period of time. There were 26 men and two women with an age range of 26-66 years (mean = 42.1). Twenty-six patients had alcohol abuse as the cause of pancreatitis; two were due to surgical trauma. Nondilated pancreatic ducts were demonstrated in 25 patients. Six had pancreatic ascites associated with pseudocysts. Four had previous operative drainage (2 internal and 2 external drainage procedures). Five patients received octreotide acetate, a synthetic peptide which mimics the action of somatostatin, in an attempt to aid closure of external fistulas. The mean length of catheter drainage was 48 days (range 7-210 days). Eight (29%) patients developed procedure-related complications (1 pneumothorax, 1 sheared guidewire, six drain tract infections). There was no mortality. Successful resolution of pseudocysts was achieved in 26 patients (93%). Two patients subsequently had elective caudal pancreaticojejunostomy (CPJ), and one lateral pancreaticojejunostomy (LPJ) to drain obstructed pancreatic ducts. One patient has required repeat external drainage. Percutaneous external drainage is successful in pseudocyst eradication. When underlying pancreatic pathology remains uncorrected, elective surgical decompression of obstructed, dilated ducts may be necessary.
胰腺假性囊肿是重症胰腺炎的一种并发症。尽管手术引流是治疗假性囊肿的基石,但在1982年至1988年的六年时间里,我们对一组经过挑选的28例患者进行了经皮导管引流。这占高级作者治疗的假性囊肿患者的42%,占该时期医科大学附属医院胰腺炎住院患者的1.7%。患者中有26名男性和2名女性,年龄在26至66岁之间(平均42.1岁)。26例患者因酗酒导致胰腺炎;2例因手术创伤所致。25例患者显示胰管未扩张。6例患者伴有与假性囊肿相关的胰性腹水。4例患者曾接受过手术引流(2例为内引流,2例为外引流)。5例患者接受了醋酸奥曲肽治疗,醋酸奥曲肽是一种模拟生长抑素作用的合成肽,旨在帮助闭合外瘘。导管引流的平均时间为48天(范围7至210天)。8例(29%)患者出现与操作相关的并发症(1例气胸,1例导丝折断,6例引流管通道感染)。无死亡病例。26例患者(93%)假性囊肿成功消退。2例患者随后接受了择期胰尾胰空肠吻合术(CPJ),1例接受了侧方胰空肠吻合术(LPJ)以引流梗阻的胰管。1例患者需要再次进行外引流。经皮外引流在根除假性囊肿方面是成功的。当潜在的胰腺病变未得到纠正时,可能需要对梗阻、扩张的胰管进行择期手术减压。