Zare Marc M, Itani Kamal M F, Schifftner Tracy L, Henderson William G, Khuri Shukri F
Department of Surgery, Boston VA Healthcare System, West Roxbury, Massachusetts, USA.
Ann Surg. 2007 Nov;246(5):866-74. doi: 10.1097/SLA.0b013e3180cc2e60.
To determine whether nonemergent major surgery leads to higher mortality when performed on Friday versus early weekdays.
Adults admitted emergently to acute-care hospitals on weekends experience higher mortality than those admitted on weekdays.
Cohort study of 188,212 patients undergoing nonemergent major surgery at 124 Veterans Affairs hospitals from 2000 to 2004. Risk-adjusted 30-day mortality was compared for operations performed on Fridays versus Mondays through Wednesdays. Data were derived from the Veterans Affairs' National Surgical Quality Improvement Program database. Patients were divided into 3 groups: floor (admitted postoperatively to regular floor), ICU (admitted postoperatively to intensive care unit), and outpatient (not admitted postoperatively). A stepwise logistic regression analysis was used to test the effect of day of surgery (Friday vs. Monday-through-Wednesday) on 30-day mortality in the presence of characteristics that were significant in bivariate analysis.
In the floor group (n = 89,786), operations performed on Fridays were associated with a higher 30-day mortality rate than those performed on Mondays through Wednesdays (2.94% vs. 2.18%; odds ratio, 1.36; 95% confidence interval, 1.24-1.49; P < 0.001). After adjusting for patient characteristics, odds ratio of 30-day mortality for operations on Fridays, when compared with Mondays through Wednesdays, was 1.17 (95% confidence interval, 1.05-1.26; P = 0.003). Within the ICU (n = 14,271) and outpatient (n = 84,155) groups, nonsignificant differences in 30-day mortality were observed for operations on Fridays versus Mondays through Wednesdays.
For patients admitted to regular hospital floors after nonemergent major surgery, mortality is increased if surgery is performed on Friday versus Monday through Wednesday.
确定非急诊大手术在周五进行与在工作日早期进行相比是否会导致更高的死亡率。
周末急诊入院至急症医院的成年人死亡率高于工作日入院者。
对2000年至2004年在124家退伍军人事务医院接受非急诊大手术的188,212例患者进行队列研究。比较周五与周一至周三进行手术的风险调整后30天死亡率。数据来源于退伍军人事务部的国家外科质量改进计划数据库。患者分为3组:普通病房组(术后入住普通病房)、重症监护病房组(术后入住重症监护病房)和门诊组(术后不住院)。采用逐步逻辑回归分析,在双变量分析中有显著意义的特征存在的情况下,检验手术日(周五与周一至周三)对30天死亡率的影响。
在普通病房组(n = 89,786)中,周五进行的手术与周一至周三进行的手术相比,30天死亡率更高(2.94%对2.18%;比值比,1.36;95%置信区间,1.24 - 1.49;P < 0.001)。在调整患者特征后,周五手术与周一至周三手术相比,30天死亡率的比值比为1.17(95%置信区间,1.05 - 1.26;P = 0.003)。在重症监护病房组(n = 14,271)和门诊组(n = 84,155)中,周五与周一至周三进行的手术在30天死亡率方面未观察到显著差异。
对于非急诊大手术后入住普通医院病房的患者,周五进行手术与周一至周三进行手术相比,死亡率会增加。