环核苷酸对血管平滑肌蛋白质合成的影响。
Influence of cyclic nucleotides on protein synthesis in vascular smooth muscle.
作者信息
Andersson R G, Arnqvist H J, Lundholm L
出版信息
Experientia. 1976 May 15;32(5):601-2. doi: 10.1007/BF01990186.
PMID:179841
Abstract
The incorporation of leucine-14C into protein in bovine mesenteric arteries was augmented by cyclic GMP (10-3 M) and decreased by cyclic AMP (10-3 M). There was no effect of 5'AMP (10-3 M). The phosphodiesterase inhibiting drugs theophylline (10-3 M) and papaverine (5 x 10-5 g/ml) both decreased the leucine-14C incorporation.
摘要
环磷酸鸟苷（10⁻³M）可增强牛肠系膜动脉中亮氨酸 - ¹⁴C掺入蛋白质的过程，而环磷酸腺苷（10⁻³M）则使其降低。5'-腺苷酸（10⁻³M）无此作用。磷酸二酯酶抑制药物茶碱（10⁻³M）和罂粟碱（5×10⁻⁵g/ml）均降低亮氨酸 - ¹⁴C的掺入。
Zotero 插件