儿童和青少年2型糖尿病的合并症及微血管并发症

Comorbidities and microvascular complications of type 2 diabetes in children and adolescents.

作者信息

Dean Heather J, Sellers Elizabeth A C

机构信息

Department of Pediatrics & Child Health, Faculty of Medicine, University of Manitoba, Winnipeg, Manitoba, Canada.

出版信息

Pediatr Diabetes. 2007 Dec;8 Suppl 9:35-41. doi: 10.1111/j.1399-5448.2007.00340.x.

DOI:10.1111/j.1399-5448.2007.00340.x

PMID:17991131

Abstract

The comorbidities of type 2 diabetes in children and adolescents are mainly related to coexistent insulin resistance and compounded by poverty. The prevalence of dyslipidemia, fatty liver, and hypertension may not be higher than the rates in obese children and adolescents, but the stakes are higher in children with diabetes because the diabetes confers a higher cardiovascular risk. This risk is exaggerated further in children with poor hygiene, smoking, and primary renal disease. Sexuality, contraception, preconception counseling, and psychiatric conditions require unique considerations in youth with type 2 diabetes.

摘要

儿童和青少年2型糖尿病的合并症主要与并存的胰岛素抵抗有关，并因贫困而加剧。血脂异常、脂肪肝和高血压的患病率可能并不高于肥胖儿童和青少年，但糖尿病儿童的风险更高，因为糖尿病会带来更高的心血管风险。在卫生条件差、吸烟和患有原发性肾病的儿童中，这种风险会进一步加剧。对于患有2型糖尿病的青少年，性、避孕、孕前咨询和精神状况需要特别考虑。