异基因外周血干细胞移植后嗜酸性粒细胞性毛囊炎：病例报告及文献复习

Eosinophilic folliculitis following allogeneic peripheral blood stem cell transplantation: case report and review.

作者信息

Goiriz Rebeca, Guhl-Millán Guillermo, Peñas Pablo F, Fernández-Herrera Jesús, Daudén Esteban, Fraga Javier, García-Diez Amaro

机构信息

Department of Dermatology, Hospital Universitario La Princesa, Madrid, Spain.

出版信息

J Cutan Pathol. 2007 Dec;34 Suppl 1:33-6. doi: 10.1111/j.1600-0560.2006.00725.x.

DOI:10.1111/j.1600-0560.2006.00725.x

PMID:17997736

Abstract

Eosinophilic folliculitis is considered a heterogeneous group of disorders, with several clinical subsets, sharing a common histopathological appearance. Increasing numbers of cases, following bone marrow transplantation (BMT), have been reported in recent years. We herein present a case of eosinophilic folliculitis that appeared in a 26-year-old woman 5 months after allogeneic peripheral blood stem cell transplantation as treatment for eosinophilic acute leukemia. Our review of the published cases has shown that eosinophilic folliculitis in patients after BMT could be considered as a pattern of reaction related to immune dysregulation.

摘要

嗜酸性粒细胞性毛囊炎被认为是一组异质性疾病，有几个临床亚组，具有共同的组织病理学表现。近年来，骨髓移植（BMT）后出现此类病例的报道越来越多。我们在此报告一例嗜酸性粒细胞性毛囊炎，该病例发生在一名26岁女性身上，她在接受异基因外周血干细胞移植治疗嗜酸性粒细胞性急性白血病5个月后发病。我们对已发表病例的回顾表明，BMT后患者发生的嗜酸性粒细胞性毛囊炎可被视为一种与免疫失调相关的反应模式。