Sarna M S, Saili A, Dutta A K, Kumari S
Neonatal Division, Lady Hardinge Medical College, New Delhi.
Indian Pediatr. 1991 Jul;28(7):719-24.
Neonatal mortality rate is perhaps the most reliable indicator of the perinatal outcome. An assessment of perinatal outcome can be made through knowledge of causes of death. This study was carried out to evaluate the neonatal deaths in our hospital. Live births (n = 7309) and deaths (n = 328) during a 6 months period were retrospectively analyzed. These were grouped into non-preventable and potentially preventable causes of death. The single most important factor contributing to the mortality was respiratory distress (29.3%) followed by sepsis (24.4%) and birth asphyxia (16.2%). The non-preventable causes of mortality (e.g., lethal congenital malformations, extremely low birth weight) accounted for 10.4% of the total mortality. The idealized neonatal mortality rate was 4.6/1000 live births, while the salvageable death rate was 40.2/1000 live births. The mortality increased significantly if the birth weight fell below 2 kg. The salvageable deaths could perhaps be prevented through better antenatal and intranatal care, ventilatory support and prevention of sepsis.
新生儿死亡率可能是围产期结局最可靠的指标。通过了解死亡原因可以对围产期结局进行评估。本研究旨在评估我院的新生儿死亡情况。对6个月期间的活产儿(n = 7309)和死亡病例(n = 328)进行回顾性分析。这些病例被分为不可预防和潜在可预防的死亡原因。导致死亡的最重要单一因素是呼吸窘迫(29.3%),其次是败血症(24.4%)和出生窒息(16.2%)。不可预防的死亡原因(如致命性先天性畸形、极低出生体重)占总死亡率的10.4%。理想的新生儿死亡率为4.6/1000活产儿,而可挽救的死亡率为40.2/1000活产儿。如果出生体重低于2千克,死亡率会显著增加。通过更好的产前和产时护理、通气支持以及预防败血症,或许可以预防可挽救的死亡。