Kim Bong-Soo, Uchikawa Yoshinori
Department of Electronic and Computer Engineering, School of Science and Engineering, Tokyo Denki University, Ishizaka, Hatoyama, Hiki-gun, Saitama, Japan.
Annu Int Conf IEEE Eng Med Biol Soc. 2007;2007:6220-3. doi: 10.1109/IEMBS.2007.4353776.
Measurements of somatosensory evoked field (SEF) by median nerve stimulation and auditory evoked field (AEF) by tone burst to right ear were performed. MEG measurements of multiple sources, AEF and SEF overlapped in time, were carried out. In the mixed AEF and SEF, stimulation to the median nerve was delivered 80 and 200ms later than to the right ear, respectively. Dynamic singular value decomposition (DSVD) method, having a time window and shift time, was applied to each spatio-temporal magnetic data. It showed that the time course of the singular value corresponded to the change of magnetic field waveforms. Furthermore, in order to discuss hemispheric characteristics, the DSVD was also applied to the spatio-temporal magnetic data of bilateral hemisphere (contra and ipsilateral to the stimulation). It showed that the time course of the singular value of all magnetic data well matched to the results of the contralateral hemisphere. Correlation coefficient was calculated between the results of the DSVD in each hemisphere. The correlation coefficient of the contralateral (left) hemisphere showed a higher value than that of the ipsilateral (right, over 0.7). Finally, Time-frequency analysis was applied to the magnetic data of the contralateral hemisphere. We conclude that the DSVD, having time window and shift time, is useful for analyzing spatio-temporal activity of the human cortex.
通过正中神经刺激测量体感诱发电场(SEF),并通过对右耳进行短纯音刺激测量听觉诱发电场(AEF)。进行了多个源的脑磁图(MEG)测量,AEF和SEF在时间上重叠。在混合的AEF和SEF中,对正中神经的刺激分别比右耳刺激晚80和200毫秒。将具有时间窗口和移动时间的动态奇异值分解(DSVD)方法应用于每个时空磁数据。结果表明,奇异值的时间进程与磁场波形的变化相对应。此外,为了探讨半球特征,DSVD也应用于双侧半球(与刺激相对和同侧)的时空磁数据。结果表明,所有磁数据的奇异值时间进程与对侧半球的结果良好匹配。计算了每个半球DSVD结果之间的相关系数。对侧(左)半球的相关系数显示出比同侧(右)半球更高的值(超过0.7)。最后,对侧半球的磁数据进行了时频分析。我们得出结论,具有时间窗口和移动时间的DSVD对于分析人类皮层的时空活动是有用的。