Phipps A W, Fell T P, Harrison J D, Paquet F, Leggett R W
Radiation Protection Division, Health Protection Agency, Chilton, Didcot, Oxon OX11 0RQ, UK.
Radiat Prot Dosimetry. 2007;127(1-4):79-85. doi: 10.1093/rpd/ncm254. Epub 2007 Nov 14.
Publication 100 of the International Commission on Radiological Protection (ICRP) provides a Human Alimentary Tract Model (HATM) to replace the gastrointestinal (GI) model described in Publication 30. The HATM will be used for future calculations of dose coefficients and bioassay predictions, first in a series of publications on occupational intakes of radionuclides, and subsequently in revision of dose coefficients for public exposures. This paper compares dose coefficients calculated using the new model with current values calculated using the GI model for a range of radionuclides. Colon doses are lower using the HATM in all cases considered, in some cases by significant factors. Stomach doses tend to be lower, but are in some cases higher under HATM. The extent to which these changes in doses to gut tissues impacts upon the effective dose varies among nuclides, but there is a tendency for lower effective doses. Special-case applications of the HATM are also described, considering retention on teeth or in the walls of the small intestine. Although the effect of such retention on the regional tissue dose can be large, the effective dose is not greatly changed.
国际放射防护委员会(ICRP)第100号出版物提供了一个人体消化道模型(HATM),以取代第30号出版物中描述的胃肠道(GI)模型。HATM将用于未来剂量系数的计算和生物测定预测,首先用于一系列关于放射性核素职业摄入量的出版物中,随后用于修订公众照射的剂量系数。本文比较了使用新模型计算的剂量系数与使用GI模型针对一系列放射性核素计算的当前值。在所考虑的所有情况下,使用HATM时结肠剂量均较低,在某些情况下降低幅度很大。胃剂量往往较低,但在HATM模型下某些情况下较高。肠道组织剂量的这些变化对有效剂量的影响程度因核素而异,但有效剂量有降低的趋势。文中还描述了HATM的特殊情况应用,考虑了在牙齿或小肠壁上的滞留。尽管这种滞留对局部组织剂量的影响可能很大,但有效剂量变化不大。