尽管已进行了10年的疫苗接种，但社区获得性流感嗜血杆菌脑膜炎在儿童中仍有发生。

Haemophillus influenzae community acquired meningitis occurrence in children despite 10 years vaccination.

作者信息

Taziarova M, Holeckova K, Lesnakova A, Sladeckova V, Bartkovjak M, Seckova S, Bukovinova P, Hvizdak F, Svabova V, Findova L, Kisac P, Beno P, Bauer F, Kovac M, Karvaj M, Rudinsky B, Sabo I, Bielova M, Luzica R, Wiczmandyova O, Huttova M, Ondrusova A

机构信息

St. Elizabeth University College of Health and Social Sciences, Bratislava, Michalovce, Slovakia.

出版信息

Neuro Endocrinol Lett. 2007 Nov;28 Suppl 3:30-1.

PMID:18030275

Abstract

Despite of 10 years vaccination of all children within 1st year in Slovakia against H. influenzae, this severe infection still occurs. Among 201 cases of community acquired bacterial meningitis, 14 (7%) were caused by H. influenzae serotype B. Outcome however, after early institution of treatment was fortunately positive - only 1 patient died (7.1% mortality) and in 2 other neurologic sequellae occurred (14.3%), which were transient and mild.

摘要

尽管斯洛伐克对所有一岁以内儿童进行了十年的流感嗜血杆菌疫苗接种，但这种严重感染仍有发生。在201例社区获得性细菌性脑膜炎病例中，14例（7%）由B型流感嗜血杆菌引起。然而，早期开始治疗后的结果幸运地是积极的——只有1例患者死亡（死亡率7.1%），另外2例出现了神经后遗症（14.3%），这些后遗症是短暂且轻微的。