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英国国家医疗服务体系(NHS)卫生技术评估项目的影响评估

An assessment of the impact of the NHS Health Technology Assessment Programme.

作者信息

Hanney S, Buxton M, Green C, Coulson D, Raftery J

机构信息

Health Economics Research Group, Brunel University, Uxbridge, UK.

出版信息

Health Technol Assess. 2007 Dec;11(53):iii-iv, ix-xi, 1-180. doi: 10.3310/hta11530.

Abstract

OBJECTIVES

To consider how the impact of the NHS Health Technology Assessment (HTA) Programme should be measured. To determine what models are available and their strengths and weaknesses. To assess the impact of the first 10 years of the NHS HTA programme from its inception in 1993 to June 2003 and to identify the factors associated with HTA research that are making an impact.

DATA SOURCES

Main electronic databases from 1990 to June 2005. The documentation of the National Coordinating Centre for Health Technology Assessment (NCCHTA). Questionnaires to eligible researchers. Interviews with lead investigators. Case study documentation.

REVIEW METHODS

A literature review of research programmes was carried out, the work of the NCCHTA was reviewed, lead researchers were surveyed and 16 detailed case studies were undertaken. Each case study was written up using the payback framework. A cross-case analysis informed the analysis of factors associated with achieving payback. Each case study was scored for impact before and after the interview to assess the gain in information due to the interview. The draft write-up of each study was checked with each respondent for accuracy and changed if necessary.

RESULTS

The literature review identified a highly diverse literature but confirmed that the 'payback' framework pioneered by Buxton and Hanney was the most widely used and most appropriate model available. The review also confirmed that impact on knowledge generation was more easily quantified than that on policy, behaviour or especially health gain. The review of the included studies indicated a higher level of impact on policy than is often assumed to occur. The survey showed that data pertinent to payback exist and can be collected. The completed questionnaires showed that the HTA Programme had considerable impact in terms of publications, dissemination, policy and behaviour. It also showed, as expected, that different parts of the Programme had different impacts. The Technology Assessment Reports (TARs) for the National Institute for Health and Clinical Excellence (NICE) had the clearest impact on policy in the form of NICE guidance. Mean publications per project were 2.93 (1.98 excluding the monographs), above the level reported for other programmes. The case studies revealed the large diversity in the levels and forms of impacts and the ways in which they arise. All the NICE TARs and more than half of the other case studies had some impact on policy making at the national level whether through NICE, the National Screening Committee, the National Service Frameworks, professional bodies or the Department of Health. This underlines the importance of having a customer or 'receptor' body. A few case studies had very considerable impact in terms of knowledge production and in informing national and international policies. In some of these the principal investigator had prior expertise and/or a research record in the topic. The case studies confirmed the questionnaire responses but also showed how some projects led to further research.

CONCLUSIONS

This study concluded that the HTA Programme has had considerable impact in terms of knowledge generation and perceived impact on policy and to some extent on practice. This high impact may have resulted partly from the HTA Programme's objectives, in that topics tend to be of relevance to the NHS and have policy customers. The required use of scientific methods, notably systematic reviews and trials, coupled with strict peer reviewing, may have helped projects publish in high-quality peer-reviewed journals. Further research should cover more detailed, comprehensive case studies, as well as enhancement of the 'payback framework'. A project that collated health research impact studies in an ongoing manner and analysed them in a consistent fashion would also be valuable.

摘要

目标

探讨应如何衡量英国国家医疗服务体系健康技术评估(HTA)项目的影响。确定有哪些可用模型及其优缺点。评估英国国家医疗服务体系HTA项目自1993年启动至2003年6月的头10年的影响,并确定与产生影响的HTA研究相关的因素。

数据来源

1990年至2005年6月的主要电子数据库。国家卫生技术评估协调中心(NCCHTA)的文件。向符合条件的研究人员发放的问卷。对首席研究员的访谈。案例研究文件。

综述方法

对研究项目进行文献综述,审查NCCHTA的工作,对首席研究员进行调查,并开展16个详细的案例研究。每个案例研究都使用回报框架进行撰写。跨案例分析为与实现回报相关的因素分析提供了信息。在访谈前后对每个案例研究的影响进行评分,以评估由于访谈而获得的信息增益。每个研究的撰写草稿都与每位受访者核对准确性,并在必要时进行修改。

结果

文献综述发现了大量不同的文献,但证实由巴克斯顿和汉尼开创的“回报”框架是使用最广泛且最合适的可用模型。综述还证实,对知识生成的影响比政策、行为或特别是健康收益的影响更容易量化。对纳入研究的综述表明,对政策的影响程度高于通常认为的水平。调查显示,存在与回报相关的数据且可以收集。完成的问卷表明,HTA项目在出版物、传播、政策和行为方面产生了相当大的影响。如预期的那样,它还表明该项目的不同部分有不同的影响。国家卫生与临床优化研究所(NICE)的技术评估报告(TARs)以NICE指南的形式对政策产生了最明显的影响。每个项目的平均出版物数量为2.93篇(不包括专著为1.98篇),高于其他项目报告的水平。案例研究揭示了影响的水平、形式及其产生方式的巨大差异。所有NICE的TARs以及超过一半的其他案例研究对国家层面的政策制定都产生了一定影响,无论是通过NICE、国家筛查委员会、国家服务框架、专业机构还是卫生部。这凸显了拥有一个客户或“接受者”机构的重要性。一些案例研究在知识生产以及为国家和国际政策提供信息方面产生了非常重大的影响。在其中一些案例中,首席研究员在该主题方面有先前的专业知识和/或研究记录。案例研究证实了问卷调查的结果,但也展示了一些项目如何引发进一步的研究。

结论

本研究得出结论,HTA项目在知识生成以及对政策的感知影响和在一定程度上对实践的影响方面产生了相当大的影响。这种高影响可能部分源于HTA项目的目标,即主题往往与英国国家医疗服务体系相关且有政策客户。对科学方法(特别是系统评价和试验)的要求使用,再加上严格的同行评审,可能有助于项目在高质量的同行评审期刊上发表。进一步的研究应涵盖更详细、全面的案例研究,以及对“回报框架”的完善。一个持续整理健康研究影响研究并以一致方式进行分析的项目也将是有价值的。

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