MMWR Morb Mortal Wkly Rep. 2007 Nov 30;56(47):1237-41.
The World Health Organization (WHO) and United Nations Children's Fund (UNICEF) comprehensive strategy for measles mortality reduction is focused on 47 priority countries. Components include 1) achieving and maintaining high coverage (>90%) with the first dose of measles vaccine by age 12 months in every district of each priority country through routine immunization services; 2) ensuring that all children receive a second opportunity for measles vaccination; 3) maintaining effective case-based surveillance and monitoring of vaccination coverage; and 4) providing appropriate clinical management, including vitamin A supplementation. In 2005, the World Health Assembly set a goal for global measles control as part of the Global Immunization Vision and Strategy (GIVS): a 90% reduction in measles mortality by 2010, compared with 2000 levels. In January 2007, WHO/UNICEF reported that implementation of measles mortality reduction strategies had reduced measles mortality by 60%, from an estimated 873,000 deaths in 1999 to 345,000 deaths in 2005. This reduction exceeded the goal of 50% measles mortality reduction by 2005 (compared with 1999 levels) that had been set in 2002. This report updates previous reports by detailing 1) measles mortality reduction activities implemented during 2006 and 2) the impact of activities since 2000 on the global burden of measles and progress toward the GIVS mortality reduction goal for 2010.
世界卫生组织(WHO)和联合国儿童基金会(UNICEF)降低麻疹死亡率的综合战略聚焦于47个重点国家。其组成部分包括:1)通过常规免疫服务,在每个重点国家的每个地区,使12月龄儿童麻疹疫苗首剂接种率达到并维持在较高水平(>90%);2)确保所有儿童都有机会再次接种麻疹疫苗;3)维持有效的基于病例的监测以及对疫苗接种覆盖率的监测;4)提供适当的临床管理,包括补充维生素A。2005年,世界卫生大会设定了全球麻疹控制目标,作为全球免疫远景与战略(GIVS)的一部分:到2010年,麻疹死亡率相较于2000年水平降低90%。2007年1月,WHO/UNICEF报告称,降低麻疹死亡率战略的实施已使麻疹死亡率降低了60%,从1999年估计的87.3万例死亡降至2005年的34.5万例死亡。这一降幅超过了2002年设定的到2005年麻疹死亡率降低50%(相较于1999年水平)的目标。本报告通过详细阐述1)2006年期间实施的降低麻疹死亡率活动,以及2)自2000年以来这些活动对全球麻疹负担的影响和在实现2010年GIVS死亡率降低目标方面取得的进展,更新了以往的报告。