Borisov D B, Levin A V, Vyl'iurov I V, Sokolov A V, Nedashkovskiĭ E V
Anesteziol Reanimatol. 2007 Sep-Oct(5):38-40.
In a randomized, controlled study, 50 patients underwent elective surgery for abdominal cancer lesions under perioperative epidural analgesia. All the patients were randomized to receive paracetamol in a single intravenous dose of 1 g or placebo 30 minutes prior to the start of surgery. The use of 1 g of paracetamol as a single intravenous preemptive dose in abdominal surgery with perioperative epidural analgesia does not reduce the consumption of the analgesic and the intensity of pain in the postoperative period.
在一项随机对照研究中,50例患者在围手术期硬膜外镇痛下接受腹部癌症病变的择期手术。所有患者在手术开始前30分钟被随机分配接受单次静脉注射1克对乙酰氨基酚或安慰剂。在围手术期硬膜外镇痛的腹部手术中,使用1克对乙酰氨基酚作为单次静脉注射超前镇痛剂量并不能减少术后镇痛药物的消耗量和疼痛强度。