无自发单位放电的脑干神经元。
Brainstem neurons without spontaneous unit discharge.
作者信息
Siegel J M, McGinty D J
出版信息
Science. 1976 Jul 16;193(4249):240-2. doi: 10.1126/science.180599.
Abstract
A new class of single neurons showing no spontaneous activity in waking, rapid eye movement sleep, and slow-wave sleep was found in the brainstem of unrestrained cats. Systematic testing showed that these cells discharge only in response to specific stimuli and remain silent for as long as 40 minutes in the absence of stimulation. Silent cells were widely distributed in the pons and midbrain and constituted a major percentage of observed neurons. The economy of discharge shown by these cells contrasts with the spontaneous activity of virtually all other neurons that have been observed in the brains of unrestrained animals and suggests the widespread existence of specialized neural systems that show only phasic activity.
摘要
在未受约束的猫的脑干中发现了一类新的单神经元，这类神经元在清醒、快速眼动睡眠和慢波睡眠状态下均无自发活动。系统测试表明，这些细胞仅在对特定刺激作出反应时才放电，在无刺激的情况下可长达40分钟保持沉默。沉默细胞广泛分布于脑桥和中脑，且在观察到的神经元中占很大比例。这些细胞所表现出的放电经济性与在未受约束动物大脑中观察到的几乎所有其他神经元的自发活动形成对比，这表明广泛存在仅表现为相位性活动的特殊神经系统。
相似文献
1
Brainstem neurons without spontaneous unit discharge.无自发单位放电的脑干神经元。
Science. 1976 Jul 16;193(4249):240-2. doi: 10.1126/science.180599.
2
Influence of hypnogenic brain areas on wakefulness- and rapid-eye-movement sleep-related neurons in the brainstem of freely moving cats.催眠脑区对自由活动猫脑干中与觉醒及快速眼动睡眠相关神经元的影响。
J Neurosci Res. 2004 Jan 1;75(1):133-42. doi: 10.1002/jnr.10827.
3
Single unit recordings in the nuclei raphe dorsalis and magnus during the sleep-waking cycle of semi-chronic prepared cats.在半慢性制备的猫的睡眠-觉醒周期中，对中缝背核和中缝大核进行单神经元记录。
Neurosci Lett. 1981 Jul 2;24(2):133-8. doi: 10.1016/0304-3940(81)90236-6.
4
Activity of serotonin-containing nucleus centralis superior (Raphe medianus) neurons in freely moving cats.自由活动猫中含5-羟色胺的中缝正中核神经元的活动
Exp Brain Res. 1984;54(1):33-44. doi: 10.1007/BF00235816.
5
Brain stem gigantocellular neurons: patterns of activity during behavior and sleep in the freely moving rat.脑干巨细胞神经元：自由活动大鼠行为和睡眠期间的活动模式
J Neurophysiol. 1979 Jan;42(1 Pt 1):214-28. doi: 10.1152/jn.1979.42.1.214.
6
Dynamics of neuron spike activity in the oral nucleus of the pons during the sleep-waking cycle in cats.猫睡眠-觉醒周期中脑桥口核神经元放电活动的动态变化
Neurosci Behav Physiol. 2004 Jun;34(5):485-9. doi: 10.1023/b:neab.0000022634.17261.aa.
7
Raphe unit activity during REM sleep in normal cats and in pontine lesioned cats displaying REM sleep without atonia.正常猫和脑桥损伤后出现快速眼动睡眠但无张力缺失的猫在快速眼动睡眠期间中缝核单位活动。
Brain Res. 1981 Dec 7;226(1-2):75-91. doi: 10.1016/0006-8993(81)91084-2.
8
Sleep-waking states develop independently in the isolated forebrain and brain stem following early postnatal midbrain transection in cats.猫出生后早期进行中脑横断后，孤立的前脑和脑干中睡眠-觉醒状态会独立发展。
Neuroscience. 2001;106(4):717-31. doi: 10.1016/s0306-4522(01)00329-3.
9
Eye movement-associated discharge in brain stem neurons during desynchronized sleep.
Brain Res. 1977 Jan 31;121(1):59-76. doi: 10.1016/0006-8993(77)90438-3.
10
Activity of nucleus raphe pallidus neurons across the sleep-waking cycle in freely moving cats.自由活动猫中缝苍白核神经元在睡眠-觉醒周期中的活动。
Brain Res. 1982 Apr 8;237(1):232-7. doi: 10.1016/0006-8993(82)90572-8.
引用本文的文献
1
Pleasure, addiction, and hypocretin (orexin).愉悦、成瘾与下丘脑泌素（食欲素）。
Handb Clin Neurol. 2021;180:359-374. doi: 10.1016/B978-0-12-820107-7.00022-7.
2
The Neurobiology of Sleep and Wakefulness.睡眠与觉醒的神经生物学
Psychiatr Clin North Am. 2015 Dec;38(4):615-44. doi: 10.1016/j.psc.2015.07.002. Epub 2015 Aug 28.
3
State-related discharge of neurons in the brainstem of freely moving box turtles, Terrapene carolina major.自由活动的东部箱龟（Terrapene carolina major）脑干中与状态相关的神经元放电。
Arch Ital Biol. 2001 Feb;139(1-2):23-36.
4
The echidna Tachyglossus aculeatus combines REM and non-REM aspects in a single sleep state: implications for the evolution of sleep.针鼹（Tachyglossus aculeatus）在单一睡眠状态中结合了快速眼动（REM）和非快速眼动（non-REM）睡眠的特征：对睡眠进化的启示。
J Neurosci. 1996 May 15;16(10):3500-6. doi: 10.1523/JNEUROSCI.16-10-03500.1996.
5
Brain stem units related to movements of the pinna.与耳廓运动相关的脑干单元。
Brain Res. 1980 Nov 24;202(1):183-8.
6
Behavioral organization of reticular formation: studies in the unrestrained cat. I. Cells related to axial, limb, eye, and other movements.网状结构的行为组织：对自由活动猫的研究。I. 与轴向、肢体、眼睛及其他运动相关的细胞。
J Neurophysiol. 1983 Sep;50(3):696-716. doi: 10.1152/jn.1983.50.3.696.
7
Reticular formation neurons related to tongue movement in the behaving cat.行为猫中与舌运动相关的网状结构神经元。
Exp Neurol. 1985 Sep;89(3):689-97. doi: 10.1016/0014-4886(85)90017-2.
8
Reticulo-spinal neurons participating in the control of synergic eye and head movements during orienting in the cat. I. Behavioral properties.参与猫在定向过程中协同眼和头部运动控制的网状脊髓神经元。I. 行为特性。
Exp Brain Res. 1987;66(2):339-54. doi: 10.1007/BF00243309.
9
Anatomical distribution and response patterns of reticular neurons active in relation to acoustic startle.与听觉惊吓反应相关的活跃网状神经元的解剖分布和反应模式。
Brain Res. 1988 Aug 9;457(2):399-406. doi: 10.1016/0006-8993(88)90716-0.
10
A function for REM sleep: regulation of noradrenergic receptor sensitivity.快速眼动睡眠的一个功能：去甲肾上腺素能受体敏感性的调节。
Brain Res. 1988 Nov;472(3):213-33. doi: 10.1016/0165-0173(88)90007-0.
本文引用的文献
1
SPONTANEOUS ACTIVITY OF SINGLE VESTIBULAR NEURONS OF UNRESTRAINED CATS DURING SLEEP AND WAKEFULNESS.自由活动猫睡眠和觉醒期间单个前庭神经元的自发活动
Arch Ital Biol. 1964 Apr 18;102:308-30.
2
TEMPORAL PATTERNS OF DISCHARGE OF PYRAMIDAL TRACT NEURONS DURING SLEEP AND WAKING IN THE MONKEY.猴子睡眠和清醒时锥体束神经元放电的时间模式
J Neurophysiol. 1964 Mar;27:152-71. doi: 10.1152/jn.1964.27.2.152.
3
Transmission of information in the unanaesthetized cat's isolated forebrain.未麻醉猫离体前脑的信息传递
J Physiol. 1962 Nov;164(2):238-51. doi: 10.1113/jphysiol.1962.sp007017.
4
Reticular and thalamic multiple unit activity during wakefulness, sleep and anesthesia.
Exp Neurol. 1967 Sep;19(1):11-24. doi: 10.1016/0014-4886(67)90003-9.
5
Discharge patterns of single geniculate neurons during the rapid eye movements of sleep.
J Neurophysiol. 1966 Nov;29(6):1087-95. doi: 10.1152/jn.1966.29.6.1087.
6
The activity of single cells in the midbrain and hypothalamus of the cat during affective defense behavior.
Arch Ital Biol. 1968 Sep;106(3):243-69.
7
The informon: a network for adaptive pattern recognition.
J Theor Biol. 1970 Apr;27(1):31-67. doi: 10.1016/0022-5193(70)90128-1.
8
Changing concepts of the function of sleep: discovery of intense brain activity during sleep calls for revision of hypotheses as to its function.
Biol Psychiatry. 1969 Oct;1(4):331-48.
9
Single neuron activity in cat gigantocellular tegmental field: selectivity of discharge in desynchronized sleep.
Science. 1971 Dec 17;174(4015):1250-2. doi: 10.1126/science.174.4015.1250.
10
Selective firing by cat pontine brain stem neurons in desynchronized sleep.猫脑桥脑干神经元在去同步化睡眠中的选择性放电。
J Neurophysiol. 1974 May;37(3):497-511. doi: 10.1152/jn.1974.37.3.497.
Zotero 插件