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肾移植患者术前及术后的吸烟行为

Smoking behaviour of patients before and after renal transplantation.

作者信息

Banas Miriam C, Banas Bernhard, Wolf Johanna, Hoffmann Ute, Krüger Bernd, Böger Carsten A, Orth Stephan R, Krämer Bernhard K

机构信息

Klinik und Poliklinik für Innere Medizin II, University of Regensburg, D-93042 Regensburg, Germany.

出版信息

Nephrol Dial Transplant. 2008 Apr;23(4):1442-6. doi: 10.1093/ndt/gfm764. Epub 2007 Dec 8.

Abstract

BACKGROUND

Smoking is the most important remediable cardiovascular risk factor, and an independent risk factor for the progression of renal diseases. To date, only limited information about changes in cigarette-smoking habits before and after renal transplantation is available.

METHODS

In a comprehensive cross-sectional single centre study, we analysed smoking habits of patients registered on the waiting list for renal transplantation and patients that had received an allograft.

RESULTS

Of 230 patients (76.1%), 175 on the waiting list and of 264 allograft recipients (87.5%), 231 were non-smokers at the time of investigation (P <0.01). Among the non-smoking waiting list patients, only 71 (30.9%) had never smoked, whereas 108 (40.9%) patients of the allograft recipients were never-smokers. Of former smoking patients, 27.6% (n = 34) had stopped smoking after transplantation. Patients <55 years of age and females were more likely to stop smoking than patients >55 years of age or males. A data analysis revealed that smokers had a significantly lower probability to attain renal transplantation.

CONCLUSION

We conclude that renal transplantation is a strong incentive for patients to stop smoking. Reasons for changes in smoking behaviour after renal transplantation may be an intense contact of the patients with their physicians, the fear of a premature loss of the transplanted organ with continued smoking and the psychological support during post-transplantation patient care.

摘要

背景

吸烟是最重要的可纠正的心血管危险因素,也是肾脏疾病进展的独立危险因素。迄今为止,关于肾移植前后吸烟习惯变化的信息有限。

方法

在一项全面的单中心横断面研究中,我们分析了肾移植等待名单上患者和接受同种异体移植患者的吸烟习惯。

结果

在230名患者(76.1%)中,175名在等待名单上;在264名同种异体移植受者(87.5%)中,231名在调查时为非吸烟者(P<0.01)。在非吸烟的等待名单患者中,只有71名(30.9%)从未吸烟,而异种异体移植受者中有108名(40.9%)从未吸烟。在曾经吸烟的患者中,27.6%(n=34)在移植后戒烟。年龄<55岁的患者和女性比年龄>55岁的患者或男性更有可能戒烟。数据分析显示,吸烟者获得肾移植的概率显著较低。

结论

我们得出结论,肾移植是促使患者戒烟的有力诱因。肾移植后吸烟行为改变的原因可能是患者与医生的密切接触、担心持续吸烟会过早失去移植器官以及移植后患者护理期间的心理支持。

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