原发性震颤中报告的听力障碍：一项基于人群的病例对照研究。
Reported hearing impairment in essential tremor: a population-based case-control study.
作者信息
Benito-León Julián, Louis Elan D, Bermejo-Pareja Félix
机构信息
Department of Neurology, University Hospital 12 de Octubre, Madrid, Spain.
出版信息
Neuroepidemiology. 2007;29(3-4):213-7. doi: 10.1159/000112463. Epub 2007 Dec 13.
Abstract
In a population-based sample, we determined whether a larger proportion of essential tremor (ET) cases reported hearing impairment compared with controls. Ninety-six (38.7%) of 248 ET cases versus 1,371 (29.4%) of 4,669 controls (p = 0.002) reported hearing impairment. In a logistic regression analysis adjusted for age, gender, educational level, depressive symptoms, and dementia, participants who reported hearing impairment were 30% more likely to suffer from ET than were controls (odds ratio 1.3; 95% confidence interval 1.01-1.7; p = 0.04). ET seemed to be associated with reported hearing impairment. The basis for this finding, which has been noted in several studies, deserves further exploration.
摘要
在一个基于人群的样本中，我们确定与对照组相比，原发性震颤（ET）病例报告听力障碍的比例是否更高。248例ET病例中有96例（38.7%）报告有听力障碍，而4669例对照组中有1371例（29.4%）报告有听力障碍（p = 0.002）。在一项针对年龄、性别、教育水平、抑郁症状和痴呆进行调整的逻辑回归分析中，报告有听力障碍的参与者患ET的可能性比对照组高30%（优势比1.3；95%置信区间1.01-1.7；p = 0.04）。ET似乎与报告的听力障碍有关。这一发现的依据在多项研究中已被提及，值得进一步探究。
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