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在越南河内的低风险人群中使用商业酶免疫测定法检测抗2型单纯疱疹病毒糖蛋白G抗体。

Use of commercial enzyme immunoassays to detect antibodies to the herpes simplex virus type 2 glycoprotein G in a low-risk population in Hanoi, Vietnam.

作者信息

Ngo Thoai D, Laeyendecker Oliver, La Hanh, Hogrefe Wayne, Morrow Rhoda Ashley, Quinn Thomas C

机构信息

National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland,USA.

出版信息

Clin Vaccine Immunol. 2008 Feb;15(2):382-4. doi: 10.1128/CVI.00437-06. Epub 2007 Dec 12.

DOI:10.1128/CVI.00437-06
PMID:18077617
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2238064/
Abstract

Sera from 1,238 Vietnamese women in Hanoi were tested for herpes simplex virus type 2 (HSV-2). HSV-2 prevalence was 2.0%. The Kalon and Biokit assays showed significantly higher concordance to Western blotting data than did the Focus assay (P < 0.01). Screening by Focus and then retesting with Kalon/Biokit of positive samples can reduce falsely positive results significantly (P < 0.01).

摘要

对来自河内的1238名越南女性的血清进行了2型单纯疱疹病毒（HSV - 2）检测。HSV - 2患病率为2.0%。与焦点检测法相比，卡隆检测法和生物试剂盒检测法与蛋白质印迹数据的一致性显著更高（P < 0.01）。先用焦点检测法进行筛查，然后对阳性样本用卡隆检测法/生物试剂盒进行重新检测，可显著降低假阳性结果（P < 0.01）。

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