Yaghoubian Arezou, Lewis Roger J, de Virgilio Christian
Department of Surgery, Harbor-UCLA Medical Center, Torrance, CA.
Ann Vasc Surg. 2008 Jan;22(1):5-10. doi: 10.1016/j.avsg.2007.10.004.
The aims of this study were to determine whether National Kidney Foundation (NKF) guidelines for native arteriovenous fistula (AVF) creation (at least 50% of all new end-stage renal disease [ESRD] patients and 40% of prevalent hemodialysis patients) could be met in an underserved population who presented in late stages of ESRD. We also sought to determine 1-year AVF patency rates and factors associated with early thrombosis. One hundred seventy-six patients underwent hemodialysis access surgery during the period 2003-2005 with a mean age of 51 years. Sixty-two percent were male, and 48% had diabetes mellitus. Ultrasound vein mapping was performed in only 37%. Temporary central venous access was necessary in 109 patients (62%) due to late presentation. Of the 160 patients who were first-time access, 137 (86%) received a native AVF and 23 (14%) had an arteriovenous graft. There was a higher rate of AVF creation in males (91% vs. 75% for females, p = 0.005). The 1-year primary patency was 90%. There were no differences in early thrombosis or 1-year patency rates with respect to gender, age, ethnicity, insurance status, presence of temporary access, or use of preoperative vein mapping. In an underserved population, NKF guidelines for native AVF for first-time access can be superseded with an excellent 1-year patency, despite late presentation.
本研究的目的是确定在终末期肾病(ESRD)晚期就诊的医疗服务不足人群中,是否能够达到美国国家肾脏基金会(NKF)关于自体动静脉内瘘(AVF)创建的指南要求(所有新增终末期肾病患者的至少50%以及现有血液透析患者的40%)。我们还试图确定AVF的1年通畅率以及与早期血栓形成相关的因素。2003年至2005年期间,176例患者接受了血液透析通路手术,平均年龄为51岁。62%为男性,48%患有糖尿病。仅37%的患者进行了超声静脉造影。由于就诊较晚,109例患者(62%)需要临时中心静脉通路。在160例首次建立通路的患者中,137例(86%)接受了自体AVF,23例(14%)接受了动静脉移植物。男性的AVF创建率更高(男性为91% vs. 女性为75%,p = 0.005)。1年的初始通畅率为90%。在早期血栓形成或1年通畅率方面,性别、年龄、种族、保险状况、是否存在临时通路或术前静脉造影的使用情况均无差异。在医疗服务不足的人群中,尽管就诊较晚,但首次建立通路的自体AVF的NKF指南仍可被出色的1年通畅率所取代。