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[激光多普勒血流灌注成像观察电针对胃缺血再灌注损伤的影响研究]

[Study on effect of electroacupuncture on gastric ischemia-reperfusion by laser Doppler blood perfusion imaging].

作者信息

Zhang Dong, Li Shun-Yue, Ma Hui-Min, Wang Shu-You

机构信息

Institute of Acupuncture and Moxibustion, China Academy of Chinese Medical Sciences, Beijing 100700, China.

出版信息

Zhongguo Zhen Jiu. 2007 Nov;27(11):833-8.

Abstract

OBJECTIVE

To observe effects of electroacupuncture (EA) on gastric blood perfusion and search for a study method reflecting changes of blood perfusion.

METHODS

On the basis of establishing a new gastric ischemia-reperfusion model which was made by ligature of gastric right artery, EA was given at "Zusanli" (ST 36) and the gastric blood perfusion images were displayed by a laser Doppler blood perfusion imager (LDPI), and effects of EA on gastric blood perfusion were analyzed.

RESULTS

(1) The image of the gastric ischemia-reperfusion is clear. The ischemic degree of the stomach in the EA group was lower than the control group within 30 min of ischemia, and recovery of blood flow after perfusion in the EA group was better than the control group; (2) at 25 min of ligature, there was a significant difference in changes of blood perfusion between the EA group [(-0.50 +/- 0.18) PU] and the control group [(-0.90 +/- 0.16) PU], P < 0.05.

CONCLUSION

EA can improve and promote gastric blood supply in the gastric ischemia-reperfusion model, which can be used for acupuncture and moxibustion experimental study.

摘要

目的

观察电针(EA)对胃血液灌注的影响,并探寻一种反映血液灌注变化的研究方法。

方法

在通过结扎胃右动脉建立新的胃缺血-再灌注模型的基础上,针刺“足三里”(ST 36)并采用激光多普勒血流灌注成像仪(LDPI)显示胃血液灌注图像,分析电针(EA)对胃血液灌注的影响。

结果

(1)胃缺血-再灌注图像清晰。电针组在缺血30分钟内胃缺血程度低于对照组,电针组灌注后血流恢复情况优于对照组;(2)结扎25分钟时,电针组[(-0.50±0.18)PU]与对照组[(-0.90±0.16)PU]血液灌注变化有显著差异,P<0.05。

结论

电针可改善和促进胃缺血-再灌注模型中的胃血液供应,可用于针灸实验研究。

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