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拇外翻手术后疼痛管理的多模式镇痛:一项关于踝关节阻滞效果的前瞻性随机研究

Multi-modal-analgesia for pain management after Hallux Valgus surgery: a prospective randomised study on the effect of ankle block.

作者信息

Turan Ibrahim, Assareh Hamid, Rolf Christer, Jakobsson Jan

机构信息

Karolinska Institutet, Foot & Ankle Surgical Centre, Stockholm, Sweden.

出版信息

J Orthop Surg Res. 2007 Dec 18;2:26. doi: 10.1186/1749-799X-2-26.

Abstract

BACKGROUND

Pain and emesis are the two major complaints after day case surgery. Local anaesthesia has become an important part of optimizing intra and post-operative pain treatment, but is sometimes not entirely sufficient. The aim of the present study was to study the effect of adding an ankle block to a multi-modal analgesic approach on the first 24-hour-need for rescue analgesia in patients undergoing elective Hallux Valgus surgery.

TYPE OF STUDY

Prospective, randomized patient-blind study comparing ankle block with levo-bupivacaine, lidocaine and Saline placebo control.

METHODS

Ninety patients were studied comparing ankle block (15 cc) using levo-bupivacaine 2.5 mg/ml, lidocaine 10 mg/ml or placebo (saline) on day-case elective Hallux Valgus surgery, supported by general anaesthesia in all cases. Primary study endpoint was number of patient's requiring oral analgesics during the first 24 post-operative hours.

RESULTS

Ankle block had no effect on need for rescue analgesia and pain ratings during the 1st 24 postoperative hours, there was no difference seen between placebo and any of the two active local anaesthesia studied. The only differences seen was that both lidocaine and levo-bupivacaine reduced the intra-operative need for anaesthetic (sevoflurane) and that levo-bupivacaine patients had a lower need as compared to the lidocaine patients for oral analgesics during the afternoon of surgery.

CONCLUSION

Adding a single shot ankle block to a multi-modal pain management strategy reduces the need for intra-operative anaesthesia but has no major impact of need of rescue analgesics or pain during the first 24-hour after surgery.

摘要

背景

疼痛和呕吐是日间手术术后的两大主要主诉。局部麻醉已成为优化术中及术后疼痛治疗的重要组成部分,但有时并不完全足够。本研究的目的是探讨在多模式镇痛方法中加用踝关节阻滞对择期拇外翻手术患者术后24小时内急救镇痛需求的影响。

研究类型

前瞻性、随机、患者盲法研究,比较左旋布比卡因、利多卡因踝关节阻滞与生理盐水安慰剂对照。

方法

对90例择期日间拇外翻手术患者进行研究,所有病例均在全身麻醉支持下,比较使用2.5mg/ml左旋布比卡因、10mg/ml利多卡因或安慰剂(生理盐水)进行踝关节阻滞(15ml)的效果。主要研究终点是术后24小时内需要口服镇痛药的患者数量。

结果

踝关节阻滞对术后24小时内的急救镇痛需求和疼痛评分没有影响,安慰剂与所研究的两种有效局部麻醉剂之间没有差异。唯一的差异是,利多卡因和左旋布比卡因均减少了术中麻醉剂(七氟醚)的需求,并且与利多卡因组患者相比,左旋布比卡因组患者在手术当天下午对口服镇痛药的需求较低。

结论

在多模式疼痛管理策略中加用单次踝关节阻滞可减少术中麻醉需求,但对术后24小时内的急救镇痛需求或疼痛没有重大影响。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/04a2/2175499/0e4f4db21a75/1749-799X-2-26-1.jpg

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