高碘酸锂对结晶牛血清白蛋白的作用。
The effect of lithium periodate on crystalline bovine serum albumin.
作者信息
GOEBEL W F, PERLMANN G E
出版信息
J Exp Med. 1949 May;89(5):479-89. doi: 10.1084/jem.89.5.479.
Abstract
A study of the chemical, physicochemical, and immunological changes in bovine serum albumin, brought about by oxidation with lithium periodate, has been made. It has been shown that destruction of certain amino acids occurs, that a change in the absorption spectrum takes place, and that the electrophoretic behavior of the protein is altered. Prolonged contact of bovine albumin with lithium periodate destroys its ability to incite antibodies in experimental animals.
摘要
对高碘酸锂氧化牛血清白蛋白所引起的化学、物理化学及免疫学变化进行了一项研究。结果表明，某些氨基酸遭到破坏，吸收光谱发生变化，且蛋白质的电泳行为也有所改变。牛白蛋白与高碘酸锂长时间接触会破坏其在实验动物体内激发抗体的能力。
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