Chen Yan, Perl Yehoshua, Geller James, Hripcsak George, Zhang Li
New Jersey Institute of Technology, Newark, NJ 07102, USA.
J Biomed Inform. 2008 Apr;41(2):293-317. doi: 10.1016/j.jbi.2007.11.001. Epub 2007 Nov 17.
A metaschema is an Abstraction Network of the UMLS's Semantic Network (SN) obtained from a connected partition into its collections of semantic types. A metaschema can support comprehension, visualization and navigation of the SN. In this paper, a methodology is presented to evaluate and compare two given metaschemas, based on their structural properties. This methodology was applied to the top-down metaschema and the bottom-up metaschema, derived from two studies involving two groups of UMLS experts. By the Cronbach alpha estimate, the bottom-up metaschema is reliable, while the top-down metaschema is not. An algorithm was designed to yield a consolidated metaschema enjoying the best and avoiding the worst of the two given metaschemas. The consolidation algorithm was applied to the above two metaschemas, The resulting consolidated metaschema has better structural properties than either of the two metaschemas and better supports user orientation visualization, and navigation of the Semantic Network.
元模式是从统一医学语言系统(UMLS)语义网络(SN)的连接分区中获得的语义类型集合的抽象网络。元模式可以支持对语义网络的理解、可视化和导航。本文提出了一种基于其结构属性来评估和比较两个给定元模式的方法。该方法应用于自上而下的元模式和自下而上的元模式,这两种模式源自涉及两组UMLS专家的两项研究。通过克朗巴哈α系数估计,自下而上的元模式是可靠的,而自上而下的元模式则不可靠。设计了一种算法来生成一个综合元模式,该模式兼具两个给定元模式的优点,同时避免其缺点。该合并算法应用于上述两个元模式,所得的综合元模式具有比两个元模式中任何一个都更好的结构属性,并且能更好地支持用户对语义网络的定向可视化和导航。