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选择性监测结肠镜检查在腹主动脉瘤破裂修复成功后结肠缺血早期诊断中的可靠性

Reliability of selective surveillance colonoscopy in the early diagnosis of colonic ischemia after successful ruptured abdominal aortic aneurysm repair.

作者信息

Megalopoulos Angelos, Vasiliadis Konstantinos, Tsalis Konstantinos, Kapetanos Dimitrios, Bitzani Militsa, Tsachalis Theodor, Batziou Eleni, Botsios Dimitrios

机构信息

4th Surgical Department, Aristotle University of Thessaloniki, General Regional Hospital George Papanikolaou, Thessaloniki, Greece.

出版信息

Vasc Endovascular Surg. 2007;41(6):509-15. doi: 10.1177/1538574407306797.

Abstract

PURPOSE

To evaluate the reliability of selective surveillance colonoscopy based on 6 specific perioperative risk factors in the early diagnosis of colonic ischemia (CI) after successful ruptured abdominal aortic aneurysm (rAAA) repair.

PATIENTS AND METHODS

From 1999 to 2005, 62 consecutive patients underwent rAAA repair. In 59 of them, routine aggressive surveillance colonoscopy was offered every 12 hours within the first 48 hours, and CI was graded consistently. Patients with stage I or stage II CI were treated conservatively and were followed up with repeat colonoscopy, whereas patients with stage III CI underwent immediate laparotomy and colectomy. In parallel, 6 specific perioperative risk factors (PRFs) were retrospectively analyzed.

RESULTS

Overall mortality was 33.9%. Nineteen patients (32.2%) developed CI and 12 (63.2%) of them survived. Thirteen (22%) had grade III CI and among these 6 survived. In patients with CI the mortality rate was 36.2%. Patients with less than 3 PRFs had no CI whereas all instances of CI could be diagnosed if colonoscopy was offered selectively in patients with more than 3 PRFs. The positive predictive value of CI increased with the number of PRFs. Patients with 5 or 6 PRFs were about 101 times more likely to develop CI compared with patients with 0 to 4 PRFs (P<.001).

CONCLUSION

Our study showed that CI is a frequent complication after successful rAAA repair and could reliably be early diagnosed if surveillance colonoscopy was offered selectively in patients with more than three PRFs.

摘要

目的

基于6种特定围手术期危险因素评估选择性监测结肠镜检查在腹主动脉瘤破裂(rAAA)修复成功后早期诊断结肠缺血(CI)中的可靠性。

患者与方法

1999年至2005年,62例连续患者接受了rAAA修复。其中59例患者在术后48小时内每12小时进行一次常规积极的监测结肠镜检查,并对CI进行一致分级。I期或II期CI患者接受保守治疗并通过重复结肠镜检查进行随访,而III期CI患者则立即接受剖腹手术和结肠切除术。同时,对6种特定围手术期危险因素(PRF)进行回顾性分析。

结果

总死亡率为33.9%。19例患者(32.2%)发生CI,其中12例(63.2%)存活。13例(22%)为III期CI,其中6例存活。CI患者的死亡率为36.2%。PRF少于3个的患者未发生CI,而在PRF多于3个的患者中选择性进行结肠镜检查可诊断出所有CI病例。CI的阳性预测值随PRF数量增加。与PRF为0至4个的患者相比,PRF为5或6个的患者发生CI的可能性高约101倍(P<0.001)。

结论

我们的研究表明,CI是rAAA修复成功后的常见并发症,如果对PRF多于3个的患者选择性进行监测结肠镜检查,则可可靠地早期诊断。

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