Recurrent restenosis after implantation of sirolimus-eluting stents in aorto-ostial lesions: successful treatment with polytetrafluoroethylene-covered stents.

We describe three cases of aorto-ostial lesions with recurrent restenosis after multiple modalities of percutaneous treatment, including sirolimus-eluting stent implantation in all cases and intravascular brachytherapy in one case. In-stent restenosis was successfully managed with polytetrafluoroethylene-covered stents. Six-month angiographic follow-up documented complete patency of the target segment in all patients.