Whitley Richard J
The University of Alabama at Birmingham, AL 35233, USA.
Adv Exp Med Biol. 2008;609:216-32. doi: 10.1007/978-0-387-73960-1_16.
Significant progress has been made in the treatment of viral infections in children, particularly those caused by HSV, varicella-zoster virus and cytomegalovirus. While not discussed in this review, licensed therapies are available for influenza infection in children as well. However, and notably so, numerous viral diseases of children represent unmet medical needs and warrant dedicated drug discovery efforts, including hepatitis B and C, and respiratory syncytial virus, among others.
儿童病毒感染的治疗已取得显著进展,尤其是由单纯疱疹病毒、水痘-带状疱疹病毒和巨细胞病毒引起的感染。虽然本综述未对此进行讨论,但儿童流感感染也有获批的治疗方法。然而,值得注意的是,许多儿童病毒性疾病仍存在未满足的医疗需求,需要专门的药物研发努力,包括乙型和丙型肝炎、呼吸道合胞病毒等。