Lindgren U, Elmros T, Holm S E
Acta Orthop Scand. 1976 Jun;47(3):320-3. doi: 10.3109/17453677608991999.
One hundred and seven patients with closed suction wound drains after hip surgery were investigated with regard to bacteria in the drain. In one-third of the cases bacterial contamination of the wound was found. In more than half the total number of cases the bacteria in the wound were not identical with those found on the skin, either pre- or post-operatively. Anaerobe bacteria occurred only in one case. Penicillin administration considerably reduced the frequency of positive cultures. These findings support the prophylactic use of antibiotics in the prevention of late infections in endoprosthesis operations even when the early infection rate is satisfactorily low.
对107例髋关节手术后使用闭式吸引伤口引流管的患者进行了引流管细菌调查。在三分之一的病例中发现伤口有细菌污染。在超过半数的病例中,伤口中的细菌与术前或术后皮肤表面发现的细菌不同。厌氧菌仅在1例中出现。使用青霉素大大降低了阳性培养的频率。这些发现支持在假体手术中预防性使用抗生素以预防晚期感染,即使早期感染率令人满意地低。