Mapel Douglas W, Robinson Scott B, Dastani Homa B, Shah Hemal, Phillips Amy L, Lydick Eva
Lovelace Clinic Foundation, Albuquerque, NM 87106-4264, USA.
Value Health. 2008 Jul-Aug;11(4):628-36. doi: 10.1111/j.1524-4733.2007.00305.x. Epub 2008 Jan 8.
To estimate the costs of undiagnosed chronic obstructive pulmonary disease (COPD) by describing inpatient, outpatient, and pharmacy utilization in the years before and after the diagnosis.
A total of 6,864 patients who were enrolled in the Lovelace Health Plan for at least 12 months during the study period (January 1, 1999 through December 31, 2004) were identified. The first date that utilization was attributed to COPD was considered the first date of diagnosis. Each COPD case was matched to up to three age- and sex-matched controls. All utilization and direct medical costs during the study period were compiled monthly and compared based on the time before and after the initial diagnosis.
Total costs were higher by an average of $1,182 per patient in the 2 years before the initial COPD diagnosis, and $2,489 in the 12 months just before the initial diagnosis, compared to matched controls. Most of the higher cost for undiagnosed COPD was attributable to hospitalizations. Inpatient costs did not increase after the diagnosis was made, but approximately one-third of admissions after the diagnosis were attributed to respiratory disease. Outpatient and pharmacy costs did not differ substantially between cases and matched controls until just a few months before the initial diagnosis, but remained 50% to 100% higher than for controls in the 2 years after diagnosis.
Undiagnosed COPD has a substantial impact on health-care costs and utilization in this integrated managed care system, particularly for hospitalizations.
通过描述诊断前后几年的住院、门诊和药房使用情况,估算未诊断出的慢性阻塞性肺疾病(COPD)的成本。
确定了在研究期间(1999年1月1日至2004年12月31日)至少参加了12个月Lovelace健康计划的6864名患者。将首次归因于COPD的使用日期视为诊断的首次日期。每个COPD病例最多与三个年龄和性别匹配的对照进行匹配。研究期间的所有使用情况和直接医疗成本每月进行汇总,并根据初始诊断前后的时间进行比较。
与匹配的对照组相比,在初始COPD诊断前的2年中,每位患者的总成本平均高出1182美元,在初始诊断前的12个月中高出2489美元。未诊断出的COPD的大部分较高成本归因于住院治疗。诊断后住院成本没有增加,但诊断后的入院病例中约有三分之一归因于呼吸系统疾病。在初始诊断前几个月之前,病例组和匹配对照组的门诊和药房成本没有显著差异,但在诊断后的2年中仍比对照组高出50%至100%。
在这个综合管理的医疗系统中,未诊断出的COPD对医疗成本和使用情况有重大影响,尤其是对住院治疗。