da Luz Moreira A, Vogel J D, Kalady M F, Hammel J, Fazio V W
Department of Colorectal Surgery, Cleveland Clinic, 9500 Euclid Avenue, A30-262, Cleveland, Ohio 44195, USA.
Dis Colon Rectum. 2008 May;51(5):508-13. doi: 10.1007/s10350-007-9183-2. Epub 2008 Jan 29.
This study was designed to evaluate the yield and cost of fever evaluations in average-risk inpatients after elective colorectal surgery.
A 12-month, retrospective study was performed on patients who developed a postoperative fever > or = 38 degrees C after elective colorectal surgery. A positive fever evaluation was defined as a blood culture, urine culture, chest x-ray, or abdominal CT result that led to a change in patient management. Logistic regression, Fisher's exact test, and chi-squared test were used; odds ratios were calculated.
Of 133 patients, 26 percent had a positive evaluation. Blood culture, urine culture, chest x-ray, and CT were positive in 3, 8, 7, and 46 percent, respectively. Risk factors for a positive fever evaluation were temperature > or = 38.5 degrees C, fever evaluation after postoperative Day 6, and a clinical manifestation of systemic inflammatory response syndrome other than fever (all, P < 0.01). The cost per positive fever evaluation for the entire group, patients with 2 risk factors, or patients with 3 risk factors was $5,600, $4,200, and $2,140, respectively.
The current approach to fever evaluation after elective colorectal surgery is low yield and costly. High fever, late postoperative fever, and systemic inflammatory response syndrome are risk factors for a positive fever evaluation after colorectal surgery.
本研究旨在评估择期结直肠手术后平均风险住院患者发热评估的阳性率及成本。
对择期结直肠手术后体温≥38℃的患者进行为期12个月的回顾性研究。发热评估阳性定义为血培养、尿培养、胸部X线或腹部CT结果导致患者治疗方案改变。采用逻辑回归、Fisher精确检验和卡方检验;计算比值比。
133例患者中,26%的患者评估结果为阳性。血培养、尿培养、胸部X线和CT的阳性率分别为3%、8%、7%和46%。发热评估阳性的危险因素为体温≥38.5℃、术后第6天以后的发热评估以及除发热外的全身炎症反应综合征临床表现(均P<0.01)。整个组、有2个危险因素的患者或有3个危险因素的患者每次发热评估阳性的成本分别为5600美元、4200美元和2140美元。
目前择期结直肠手术后发热评估的方法阳性率低且成本高。高热、术后晚期发热和全身炎症反应综合征是结直肠手术后发热评估阳性的危险因素。