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耐甲氧西林金黄色葡萄球菌感染——医院感染控制中的影响

Methicillin resistant Staphylococcus aureus infections-implications in hospital infection control.

作者信息

Krishna B V S, Patil A, Chandrasekhar M R

机构信息

Department of Microbiology, KIMS, Hubli.

出版信息

Indian J Public Health. 2007 Jan-Mar;51(1):43-6.

Abstract

BACKGROUND

A significant part of nosocomial infections are caused by methicillin resistant Staphylococcus aureus (MRSA). Nosocomial MRSA are known to be multidrug resistant and thus difficult to treat.

METHODS

A 2 year study was conducted between January 2001 and December 2002 at Karnataka Institute of Medical Sciences Hospital, Hubli to assess the prevalence of MRSA and its antibiotic susceptibility pattern in various wards.

RESULTS

S. aureus was isolated from 714 patients, 283 (37.53%) of which exhibited methicillin resistance. Although these MRSA were multidrug resistant in all the wards, the problem was more severe in NICU and orthopedic wards.

CONCLUSION

The results highlight the need for effective implementation of infection control measures in the hospital. There is a need for the judicious use of antimicrobial agents in the hospital and outside as their indiscriminate use can exert pressure in selecting out MRSA and other multidrug resistant organisms.

摘要

背景

医院感染的很大一部分是由耐甲氧西林金黄色葡萄球菌(MRSA)引起的。已知医院内的MRSA具有多重耐药性,因此难以治疗。

方法

2001年1月至2002年12月期间,在胡布利的卡纳塔克邦医学科学研究所医院进行了一项为期两年的研究,以评估各病房中MRSA的流行情况及其抗生素敏感性模式。

结果

从714名患者中分离出金黄色葡萄球菌,其中283例(37.53%)表现出耐甲氧西林特性。尽管这些MRSA在所有病房中都具有多重耐药性,但在新生儿重症监护病房(NICU)和骨科病房问题更为严重。

结论

研究结果凸显了在医院有效实施感染控制措施的必要性。在医院内外都需要明智地使用抗菌药物,因为其滥用会在筛选出MRSA和其他多重耐药菌方面产生压力。

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