Monterrosa Alvaro, Blumel Juan E, Chedraui Peter
Department of Gynecology and Obstetrics, Facultad de Medicina, Universidad de Cartagena, Cartagena, Colombia.
Maturitas. 2008 Feb 20;59(2):182-90. doi: 10.1016/j.maturitas.2007.12.002. Epub 2008 Jan 29.
Increased frequency and severity of menopausal symptoms have been associated to black race. However, this situation has not been described in any Latin American population.
Compare frequency and severity of menopausal symptoms among Afro and non-Afro Hispanic Colombian climacteric women.
In this cross-sectional study, healthy Afro and non-Afro-Colombian women aged 40-59 years were asked to fill out the Menopause Rating Scale (MRS) questionnaire in order to compare symptom frequency and intensity.
A total of 578 women were surveyed (201 Afro-Colombian and 377 non-Afro-Colombian). Mean age of the whole sample was 47.9+/-5.9 years (median 47), with no differences among studied groups in terms of age, parity, and hormone therapy (HT) use. Intensity of menopausal symptoms, assessed with the total MRS score, was found to be significantly higher among Afro-Colombian women (10.6+/-6.7 vs. 7.5+/-5.7, p=0.0001), which was due to higher somatic and psychological subscale scores. In this group, the frequency of somatic symptoms, heart discomfort and muscle and joint problems, was found to be higher than in non-Afro-Colombian women (38.8% vs. 26.8% and 77.1% vs. 43.5%, respectively, p<0.05); equally, all items of the psychological subscale (depressive mood, irritability, anxiety and physical exhaustion) were also found to be higher among black women. On the other hand, compared to black women non-Afro-Colombian ones presented more bladder problems (24.9% vs. 14.9%, p=0.005). After adjusting for confounding factors, logistic regression analysis determined that black race increased the risk for presenting higher total MRS scorings (OR: 2.31; CI 95%: 1.55-3.45, p=0.0001).
Despite the limitations of this study, as determined with the MRS Afro-Colombian women exhibited more impaired quality of life (QoL) when compared to non-Afro-Colombian ones, due to a higher rate and severity of menopausal somatic and psychological symptoms.
更年期症状的频率和严重程度增加与黑人种族有关。然而，这种情况在任何拉丁美洲人群中都未被描述过。
比较非裔和非非裔哥伦比亚更年期妇女更年期症状的频率和严重程度。
在这项横断面研究中，年龄在40 - 59岁的健康非裔和非非裔哥伦比亚妇女被要求填写更年期评分量表（MRS）问卷，以比较症状频率和强度。
共调查了578名妇女（201名非裔哥伦比亚妇女和377名非非裔哥伦比亚妇女）。整个样本的平均年龄为47.9±5.9岁（中位数47岁），研究组在年龄、产次和激素治疗（HT）使用方面没有差异。用MRS总分评估的更年期症状强度在非裔哥伦比亚妇女中显著更高（10.6±6.7对7.5±5.7，p = 0.0001），这是由于躯体和心理子量表得分更高。在这组中，躯体症状、心脏不适以及肌肉和关节问题的频率高于非非裔哥伦比亚妇女（分别为38.8%对26.8%和77.1%对43.5%，p < 0.05）；同样，心理子量表的所有项目（抑郁情绪、易怒、焦虑和身体疲惫）在黑人妇女中也更高。另一方面，与黑人妇女相比，非非裔哥伦比亚妇女有更多膀胱问题（24.9%对14.9%，p = 0.005）。在对混杂因素进行调整后，逻辑回归分析确定黑人种族增加了MRS总分更高的风险（OR：2.31；95%CI：1.55 - 3.45，p = 0.0001）。
尽管本研究存在局限性，但通过MRS确定，与非非裔哥伦比亚妇女相比，非裔哥伦比亚妇女的生活质量（QoL）受损更多，这是由于更年期躯体和心理症状的发生率和严重程度更高。
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