Girisch M, Hofbeck M, Rauch R, Apitz C, Sieverding L
Universitätsklinik für Kinder- und Jugendmedizin, Pädiatrische Intensivstation, Tübingen.
Klin Padiatr. 2009 Jan-Feb;221(1):44-5. doi: 10.1055/s-2007-984371. Epub 2008 Feb 1.
Dimenhydrinate overdosage in a 3(1/2) year-old-girl with dilative cardiomyopathy. Dimenhydrinate (Vomex(R)) is frequently used in the treatment of sickness and vomiting. The symptoms of overdosage present like an anticholinergic syndrome. We report on the clinical findings of an intoxication with dimenhydrinate in a 3(1/2) year-old-girl with functional dilative cardiomyopathy following a congenital left ventricular diverticle. Especially in small children, with the application of 40 mg suppositories once or twice per day the maximum dose of 3.75 mg/kgBW/d is achieved.
一名3岁半患有扩张型心肌病的女童发生茶苯海明过量。茶苯海明(晕海宁)常用于治疗恶心和呕吐。过量症状表现为抗胆碱能综合征。我们报告了一名3岁半患有功能性扩张型心肌病的女童,在先天性左心室憩室后发生茶苯海明中毒的临床 findings。特别是在幼儿中,每天使用一次或两次40毫克栓剂可达到最大剂量3.75毫克/千克体重/天。 (注:原文中“findings”翻译为“发现”更合适,但按照要求保留英文未翻译完整,这里可根据实际情况补充完整译文使其更通顺准确)
一名3岁半患有扩张型心肌病的女童发生茶苯海明过量。茶苯海明(晕海宁)常用于治疗恶心和呕吐。过量症状表现为抗胆碱能综合征。我们报告了一名3岁半患有功能性扩张型心肌病的女童,在先天性左心室憩室后发生茶苯海明中毒的临床发现。特别是在幼儿中,每天使用一次或两次40毫克栓剂可达到最大剂量3.75毫克/千克体重/天。