Rose Michelle D, Mattoon John S, Gemensky-Metzler Ann J, Wilkie David A, Rajala-Schultz Päivi J
Department of Veterinary Clinical Sciences, College of Veterinary Medicine, The Ohio State University, Columbus, OH 43210, USA.
Am J Vet Res. 2008 Feb;69(2):279-88. doi: 10.2460/ajvr.69.2.279.
To compare the iridocorneal angle (ICA) and angle opening distance (AOD) in dogs with cataractous and noncataractous lenses; evaluate cataractous eyes ultrasono-graphically for association of postoperative ocular hypertension (POH) with the ICA, AOD, and postoperative echogenic anterior chamber debris; and evaluate intraobserver reliability associated with ICA and AOD measurements.
56 dogs with 102 cataracts, and 23 clinically normal dogs.
Ultrasound biomicroscopy was performed on 102 eyes of 56 dogs before and after cataract surgery and on 46 nondilated and dilated eyes of 23 clinically normal dogs. Cataract stage, ICA, AOD, and association with POH were assessed.
Cataract stage and ICA or AOD were not significantly associated; however, ICA and AOD typically decreased with increasing cataract maturity. Before and after pupillary dilation, AODs were significantly smaller in cataractous eyes than in noncataractous eyes. Before surgery, ICA and AOD in eyes without pupillary dilation were significantly associated with POH. At > 13 degrees , odds of developing POH increased by 11% for each degree increase in the ICA. Postoperative anterior chamber debris was not associated with POH. Coefficient of variation for repeated measurements was 10% for the ICA and 9.5% for the AOD, suggesting good intraobserver reliability.
In this study, dogs with larger ICA and AOD measurements before surgery were at greater risk of developing POH. This information may be useful for future studies to determine whether preventative treatment for POH administered prior to surgery may be beneficial.
比较患有白内障和未患白内障犬的虹膜角膜角(ICA)和房角开放距离(AOD);超声检查白内障眼,评估术后高眼压(POH)与ICA、AOD及术后前房内回声性碎屑的相关性;评估ICA和AOD测量的观察者内可靠性。
56只患有102只白内障的犬,以及23只临床正常的犬。
对56只犬的102只眼睛在白内障手术前后进行超声生物显微镜检查,并对23只临床正常犬的46只未散瞳和散瞳眼睛进行检查。评估白内障分期、ICA、AOD以及与POH的相关性。
白内障分期与ICA或AOD无显著相关性;然而,ICA和AOD通常随白内障成熟度增加而降低。瞳孔散大前后,白内障眼的AOD明显小于非白内障眼。手术前,未散瞳眼中的ICA和AOD与POH显著相关。当ICA>13度时,ICA每增加1度,发生POH的几率增加11%。术后前房碎屑与POH无关。ICA重复测量的变异系数为10%,AOD为9.5%,表明观察者内可靠性良好。
在本研究中,手术前ICA和AOD测量值较大的犬发生POH的风险更高。该信息可能有助于未来研究确定术前给予POH预防性治疗是否有益。